Results 61 to 70 of about 1,244,520 (299)

Research progress and research prospects for configuration method of flexible AC transmission system device

Energy Reports, 2021
Flexible AC transmission system (FACTS) has become the main development direction of power system in the future, so scientific configuration method of FACTS device is very important.
Bo Yuan
doaj   +1 more source

Design of a Quantum Source of High-Frequency Gravitational Waves (HFGW) and Test Methodology

, 2004
The generation of High-Frequency Gravitational Waves (HFGW) has been identified as the required breakthrough that will lead to new forms of space propulsion. Many techniques have been devised to generate HFGW, but most of them exhibit marginal efficiency,
Fontana, Giorgio
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Research of Mine-used 3.3 kV Static Var Compensator Based on SVG

Gong-kuang zidonghua, 2011
For problems of large voltage fluctuation, low power factor, large line loss, difficult starting of device and so on of power supply system in working face, the paper proposed a technical route of var compensation which takes SVG as a core, and ...
ZHAO Zeng-yu, MA Gang, ZHU Nai-peng
doaj  

Reported patterns of vaping to support long-term abstinence from smoking: a cross-sectional survey of a convenience sample of vapers

Harm Reduction Journal, 2020
Background E-cigarettes are the most popular aid to smoking cessation attempts in England and the USA. This research examined associations between e-cigarette device characteristics and patterns of use, tobacco-smoking relapse, and smoking abstinence ...
Sarah Victoria Gentry, Emma Ward, Lynne Dawkins, Richard Holland, Caitlin Notley   +4 more
doaj   +1 more source

Effectiveness Analysis of a Two Non-Identical Unit Standby System with Switching Device and Proviso of Rest [PDF]

International Journal of Mathematical, Engineering and Management Sciences, 2019
This paper deals with two-unit cold standby system with switching device and proviso of rest. The system consists of two non-identical units which are connected in parallel redundancy.
Darpandeep Kour, J. P. Singh Joorel, Neha Sharma   +2 more
doaj   +1 more source

Starting device with a molecular energy store

Izvestiya MGTU MAMI, 2015
The article presents the classification of auxiliary power sources and starters, sets out the basic requirements for them. The authors revealed the possibilities and prospects for use of molecular energy storage as a part of starters. Described are the developed portable starting device PPU-14 and test results.
S. A Lebedev, D. A Gavritskiy, V. S Antipenko   +2 more
openaire   +1 more source

First-Principles Based Matrix-Green's Function Approach to Molecular Electronic Devices: General Formalism

, 2001
Transport in molecular electronic devices is different from that in semiconductor mesoscopic devices in two important aspects: (1) the effect of the electronic structure and (2) the effect of the interface to the external contact. A rigorous treatment of
Albright, Andersen, Aulbur, Aviram, Baerends, Bormet, Brivio, Büttiker, Büttiker, Caroli, Chelikowsky, Chen, Collier, Danielewicz, Datta, Datta, Dederichs, Dekker, Di Ventra, Dorogi, Dreizler, Elstner, Emberley, Emberley, Feibelman, Feibelman, Ferrante, Ferry, Feynman, Frisch, Gimzewski, Goldhaber-Gordon, Goringe, Gross, Gunnarson, Hall, Haug, Hedin, Hershfield, Hirose, Hoffmann, Hoffmann, Joachim, Joachim, Joachim, Jones, Kadanoff, Keldysh, Kruger, Lake, Landauer, Lang, Lang, Lang, Lang, Lang, Lang, Langreth, Larade, Lundstrom, Lyo, Magoga, Mark A. Ratner, McWeeny, Meir, Meir, Metzger, Mujica, Mujica, Ness, Nitzan, Parr, Perdew, Petrov, Pople, Porath, Reed, Reed, Saito, Scheffler, Stowasser, Supriyo Datta, Tans, Taylor, Tian, Trioni, Wachutkal, Wan, Williams, Wilson, Xue, Xue, Xue, Yaliraki, Yongqiang Xue, Zeller   +95 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source