Results 111 to 120 of about 10,193,097 (251)

Performance modelling of windmilling gas turbines [PDF]

open access: yes, 2002
This thesis presents work carried out with the aim of improving the modelling of windmilling in gas turbine performance. The work also examines the phenomenon of relight.
Jones, Geoffrey B.
core   +1 more source

A study using Andrographis paniculata in diet on growth performance of Betong chicken: Starting period [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2007
An eight-week experiment was conducted to study using Andrographis paniculata (AP) on the growth performance of Betong chickens (0-8 weeks of age). Three hundred and fifteen head of 1 day old (mixed sex) betong chicks were randomly allotted to 7 dietary ...
Waree, W., Chanjula, P., Chatreewong, D.
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

In which rounds were the most rotations of key players made, and how did this affect physical activity? Analysis of the eight best teams of the 2018 FIFA world cup Russia

open access: yesBMC Sports Science, Medicine and Rehabilitation
Background Team management, especially player selection, rotation, and availability, are critical issues when dealing with the high demands of modern training and gameplay.
Paweł Chmura   +7 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Global Buildings Performance Network (GBPN)

open access: yes, 2015
The GBPN’s goal is to contribute to the building sector achieving its full energy savings and CO2mitigation potential of more than 2.1 Gt by 2030. The GBPN was founded in 2010 with the mandate to advance knowledge and expertise globally on building ...
Global Buildings Performance Network
core  

Home - About - Disclaimer - Privacy