Results 101 to 110 of about 104,880 (297)

Startup Lapland: opas lappilaiseen kasvuyrittäjyyteen [PDF]

open access: yes, 2017
Millainen toimintaympäristö Lappi on startup-yrittäjyydelle? Kuinka järjestää vaikkapa startup-työpajoja tai kuinka rakentaa tehokas hissipuhe? Millaista on olla startup-yrittäjä?
Harju-Myllyaho, Anu   +7 more
core  

Targeting Nupr1‐Mediated p53 Mitochondrial Sequestration Alleviates Aortic Dissection by Restoring the Gadd45b‐Dependent Survival Program

open access: yesAdvanced Science, EarlyView.
This study identifies Nupr1 as a crucial stress‐responsive orchestrator driving AD. Under severe stress, Nupr1 massively accumulates within mitochondria to sequester p53, triggering apoptosis and concurrently repressing the Gadd45b‐mediated survival program.
Xi Yang   +14 more
wiley   +1 more source

V2I-based startup assistance system at signalized intersections

open access: yesAdvances in Mechanical Engineering, 2015
Traffic delays are caused by unskilled vehicle operation and driver distraction during the startup process at signalized intersections. To address this issue, we propose a V2I-based driver assistance system that can acquire the current traffic signal ...
Jianqiang Wang   +5 more
doaj   +1 more source

Modulation of Presynaptic Inhibitory Retinal Circuits for Retinal Ganglion Cell Neuroprotection in Glaucoma

open access: yesAdvanced Science, EarlyView.
Ocular hypertension induces early hyperactivity in inner retinal inhibitory circuitry before substantial retinal ganglion cell loss. Sustained pharmacological inhibition of GABAergic/glycinergic neurotransmission and Vgat‐targeted Lin28 expression suppress this hyperactivity and improve RGC survival without reducing intraocular pressure. These findings
Eunji Hong   +7 more
wiley   +1 more source

Hybrid Spring‐Coupled Broadband Energy Harvester Integrated with CuSCN Functionalized Triboelectric Vibration Sensor for Self‐Sustainable Vehicular IoTs

open access: yesAdvanced Science, EarlyView.
A self‐sustainable vehicular vibration and indoor environment monitoring IoT platform is developed which integrates a hybrid spring‐coupled broadband energy harvester with a machine learning‐assisted PAN‐CuSCN nanofiber triboelectric vibration sensor for subtle‐to‐wide‐range vibration detection and road/speed classification.
Trilochan Bhatta   +6 more
wiley   +1 more source

Startup Process Optimization of P2P Live Streaming System

open access: yes工程科学与技术, 2013
:In order to solve the performance problems of existing P2P live streaming system in the dynamic environment, such as considerable startup delay, the node startup process was modeled to analyze the key factors, which had effects on node startup process ...
李晓林, 王劲林, 尤佳莉
doaj  

Disabling COMPASS Promoter Licensing Shifts HDAC‐Inhibited Gastric Cancer Toward Sustained Transcriptional Suppression During Recovery

open access: yesAdvanced Science, EarlyView.
Combined inhibition of the WDR5 WIN pocket and HDAC activity converts SAHA‐induced hyperacetylation into a promoter state with reduced WDR5–COMPASS association and H3K4me3. MYC/E2F‐linked nascent transcription and biosynthetic recovery are suppressed, while apoptosis and senescence‐like features increase, resulting in sustained growth inhibition in ...
Jintian Song   +8 more
wiley   +1 more source

Synergistic effects of graphene oxide loading and particle size in ice-templated carboxymethyl cellulose–based aerogels on dye removal

open access: yesScientific Reports
Sustainable carboxymethyl cellulose/graphene oxide (GO) aerogels were fabricated via epichlorohydrin cross-linking and ice-templating for effective methylene blue (MB) removal from aqueous solutions. The synergistic effects of GO loading (1, 3, and 5 wt%)
Soon Wan Kweon   +5 more
doaj   +1 more source

Lean Startup: mindset per governare le startup [PDF]

open access: yes, 2019
Le startup durante la loro crescita necessitano di un'organizzazione differente rispetto alla tradizionale: l'incertezza del mercato, i pochi fondi a disposizione e la non identificazione del mercato corretto potrebbero portare la startup a realizzare un
Filippini, Andrea
core  

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