Results 41 to 50 of about 1,816,827 (293)

An Investigation of the Effect of Entrepreneurial Ecosystem on Startups Success through the Mediating Effect of Self Efficacy, Entrepreneurial Attitude and Entrepreneurial Intention [PDF]

open access: yesSocioEconomic Challenges
Developing an effective entrepreneurial ecosystem is viewed as a regional economic development approach that focuses on developing supportive circumstances that encourage the startup's success.
Soha Amer Yassin   +3 more
doaj   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

What really matters for startups in luxury: entrepreneurial luxury excellence

open access: yes, 2020
Purpose– The purpose of this paper is to identify luxury-specific entrepreneurial success factors that, in addition to the well-established general success factors of startups, drive the performance of startups in the luxury industry.
Ehrensperger, Elena   +3 more
core   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen   +10 more
wiley   +1 more source

Studies on innovative energy startups’ topological roles and their correlation with success: based on temporal networks

open access: yesFrontiers in Physics
IntroductionInnovative energy startups are expediting the energy transition through the adoption of emerging technologies, including blockchain, fintech, artificial intelligence, and crowdfunding.
Ying Wang, Qing Guan
doaj   +1 more source

Study on leadership and innovation: clues for success in technology-related startups

open access: yesManagement Letters/Cuadernos de Gestión, 2021
This article tests different theories, as proposed by the author (Abadia 2016) and by reputed researchers such as Porter (1985), Christensen (1997) and Tellis (2006), on why some technology-related startups are successful in fast-changing environments ...
Alberto Abadía
doaj   +1 more source

Continuous Molecular Monitoring Using Electrochemical Aptamer‐Based Sensors: Remaining Challenges for Long‐Term In Vivo Deployment

open access: yesAdvanced Science, EarlyView.
Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley   +1 more source

Success and Risk Factors in the Pre-Startup Phase [PDF]

open access: yesSmall Business Economics, 2005
Why does one person actually succeed in starting a business, while a second person gives up? In order to answer this question, a sample of 517 nascent entrepreneurs (people in the process of setting up a business) was followed over a three-year period.
Van Gelderen, Marco   +2 more
openaire   +5 more sources

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

open access: yesAdvanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang   +8 more
wiley   +1 more source

A description of the development of HR Tech startups in Poland

open access: yesScientific Journal of Gdynia Maritime University, 2021
This article presents the problem of development and survival of startups providing services in the field of human resources. Research on startup success factors indicates that many variables simultaneously determine the possibility of survival in the ...
Natalia Mańkowska, Katarzyna Kamińska
doaj   +1 more source

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