Results 111 to 120 of about 490,905 (276)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. [PDF]

, 2016
Cellular amino acid uptake is critical for mTOR complex 1 (mTORC1) activation and cell proliferation. However, the regulation of amino acid uptake is not well-understood.
Braas, Daniel, Christofk, Heather R, Graeber, Thomas G, Krall, Abigail S, Xu, Shili   +4 more
core   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

Effects of starvation and refeeding on the hematological and serum parameters and body proximate composition of Caspian salmon (Salmo trutta caspius) fingerligs [PDF]

, 2016
This study was conducted to investigate the effects of periods of starvation and refeeding on some hematological, serum parameters and whole body proximate composition in Caspian salmon (Salmo trutta caspius).
Jani khalili, Kh., Oraji, H., Yeganeh, S., Zaefarian, A.   +3 more
core  

Mixing Properties of CSMA Networks on Partite Graphs [PDF]

, 2012
We consider a stylized stochastic model for a wireless CSMA network. Experimental results in prior studies indicate that the model provides remarkably accurate throughput estimates for IEEE 802.11 systems.
Borst, Sem C., van Leeuwaarden, Johan S. H., Zocca, Alessandro   +2 more
core   +3 more sources

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla Iglesias García, Jagoda Litowczenko‐Cybulska, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

The role of Tre6P and SnRK1 in maize early kernel development and events leading to stress-induced kernel abortion

BMC Plant Biology, 2017
Background Drought stress during flowering is a major contributor to yield loss in maize. Genetic and biotechnological improvement in yield sustainability requires an understanding of the mechanisms underpinning yield loss.
Samuel W. Bledsoe, Clémence Henry, Cara A. Griffiths, Matthew J. Paul, Regina Feil, John E. Lunn, Mark Stitt, L. Mark Lagrimini   +7 more
doaj   +1 more source

Limiting Accretion onto Massive Stars by Fragmentation-Induced Starvation

, 2010
Massive stars influence their surroundings through radiation, winds, and supernova explosions far out of proportion to their small numbers. However, the physical processes that initiate and govern the birth of massive stars remain poorly understood.
Appenzeller, Appenzeller, Appenzeller, Bacmann, Ballesteros-Paredes, Baraffe, Bate, Beckwith, Beuther, Beuther, Beuther, Bjorkman, Bonanos, Bonnor, Caselli, Chini, Clark, Ebert, Federrath, Fryxell, Galván-Madrid, Gammie, Girichidis, Glover, Goldreich, Goto, Heitsch, Hennebelle, Hennebelle, Jiang, Jijina, Johnstone, Johnstone, Kahn, Kandori, Keto, Keto, Keto, Klessen, Klessen, Klessen, Klessen, Klessen, Klessen, Kratter, Krumholz, Krumholz, Krumholz, Krumholz, Kuiper, Kuiper, Kurtz, Lada, Lada, Larson, Larson, Lucy, Matzner, McKee, Mordecai-Mark Mac Low, Motte, Motte, Oey, Offner, Offner, Padoan, Peters, Peters, Ralf S. Klessen, Robi Banerjee, Selman, Sigalotti, Tan, Testi, Thomas Peters, Truelove, Vázquez-Semadeni, Wise, Yorke   +78 more
core   +1 more source

Engineered Protein‐Based Ionic Conductors for Sustainable Energy Storage Applications

Advanced Materials, EarlyView.
Rational incorporation of charged residues into an engineered, self‐assembling protein scaffold yields solid‐state protein films with outstanding ionic conductivity. Salt‐doping further enhances conductivity, an effect amplified in the engineered variants. These properties enable the material integration into an efficient supercapacitor.
Juan David Cortés‐Ossa, Paolo Blesio, Marcial Fernandez‐Castro, Lisa Almonte, Maxence Fernandez, Mantas Liutkus, Perumal Pandurangan, Carlos Sabater, Aitor Villaverde, Manuel Melle‐Franco, Nurit Ashkenasy, Felipe Jiménez‐Ángeles, M. Carmen Morant‐Miñana, M. Reyes Calvo, Aitziber L. Cortajarena   +14 more
wiley   +1 more source

Effect of Surface Texturing on Friction and Film Thickness under Starved Lubrication Conditions [PDF]

, 2015
Tato disertační práce se zabývá vlivem mělkých mikro-textur na tření a tloušťku filmu v mazaných nekonformních kontaktech za extrémních podmínek a za podmínek hladovění kontaktu. Měření byla realizována na tribometru v konfiguraci ball-on-disk.
Ali, Fadi
core