Results 201 to 210 of about 643,807 (225)

The Biological Functions of the Versatile Transcription Factors STAT3 and STAT5 and New Strategies for their Targeted Inhibition

Journal of Mammary Gland Biology and Neoplasia, 2006
Signal transducers and activators of transcription (STATs) comprise a unique family of transcription factors, which transmit the interactions of cytokines, hormones and growth factors with their cell surface receptors into transcriptional programs.
Desrivieres, Sylvane, Kunz, Christian, Barash, Itamar, Vafaizadeh, Vida, Borghouts, Corina, Groner, Bernd   +5 more
openaire   +3 more sources

Regulation of the trans-activation potential of STAT5 through its DNA-binding activity and interactions with heterologous transcription factors

Growth Hormone & IGF Research, 2000
Extracellular hormones, growth factors and cytokines relay their effects on the transcription of genes through the recognition of specific receptors and intracellular signalling molecules. Signal transducers and activators of transcription (STATs) have been recognized as crucial intracellular signalling molecules. The cytokine receptor-associated Janus
B, Groner, M, Fritsche, E, Stöcklin, S, Berchtold, C, Merkle, R, Moriggl, E, Pfitzner   +6 more
openaire   +2 more sources

STAT5 promotes PD-L1 expression by facilitating histone lactylation to drive immunosuppression in acute myeloid leukemia

Signal Transduction and Targeted Therapy, 2023
, Zi-Jie Long
exaly  

TRANSCRIPTION FACTOR STAT5 PROMOTES GROWTH OF HUMAN PROSTATE CANCER CELLS IN VIVO

Journal of Urology, 2008
Ayush Dagvadorj, Robert A Kirken, James Karras, Marja T Nevalainen   +3 more
openaire   +1 more source

[Activation of transcriptional factors stat5 and stat3 during human T-lymphocyte proliferation induced by different mitogenic stimuli].

Tsitologiia, 2006
The activation of closely related transcription factors STAT5alpha and STAT5beta is one of the key signalling events during interleukin-2-dependent stage of T-lymphocyte proliferation. Here, we investigate the activation of STAT5 and STAT3 family proteins on different stages of T-cell proliferative response to various mitogenic stimuli.
I A, Karitskaia, N D, Aksenov, V V, Zenin, A L, Khaĭdukova, I I, Marakhova   +4 more
openaire   +1 more source

Transcription Factors STAT5 and STAT3

2008
Zoran Culig, Richard G. Pestell, Marja T. Nevalainen   +2 more
openaire   +1 more source

The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity

Nature Immunology, 2021
Jiajia Zhou, Ilona Kryczek, Xiong Li
exaly  

Overcoming enzalutamide-resistance by specific knockdown of transcription-factor STAT5 in prostate cancer

European Urology Supplements, 2018
C. Thomas, H. Erb, J. Bodenbender, T. Diehl, I. Tsaur, M. Gleave, Z. Culig, E. Jüngel, A. Haferkamp   +8 more
openaire   +1 more source

Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflammation

Nature Immunology, 2023
Zenia Kaul, Kalpana Manthiram, Pamela L Schwartzberg   +2 more
exaly  

The activity of transcription factor Stat5 responds to prolactin, growth hormone, and IGF-I in rat and bovine mammary explant culture.

Journal of Animal Science, 2000
J. Yang, J. Kennelly, V. E. Baracos
semanticscholar   +1 more source