Results 81 to 90 of about 752,838 (282)

The Security-Politics-Development Nexus: The Lessons of State-Building in Sub-Saharan Africa [PDF]

open access: yes
How can development policy support weak, dysfunctional or fragile states? What constitutes state fragility and what are the appropriate instruments for state-building?
Necla Tschirgi
core  

Serhii Yefremov: Epitome of the Ukrainian Revolution [PDF]

open access: yes, 2017
Yefremov’s personal characteristics exemplify the characteristic features of the Ukrainian revolution. He was an argumentative, pugnacious man, and the revolution was characterized by infighting. He was an institution builder, and that’s a key element of
Tarnawsky, Maxim
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Understanding and progressing health system decentralisation in Myanmar

open access: yesGlobal Security: Health, Science and Policy, 2020
Despite much lauded change in recent years, Myanmar’s national health system still lags behind its regional counterparts. Decades of civil war and military rule have created, at the national level, a ‘centralisation by fiat’.
Elliot Brennan, Seye Abimbola
doaj   +1 more source

'Good' state vs. 'bad' warlords? A critique of state-building strategies in Afghanistan [PDF]

open access: yes, 2004
The current Afghan government, having weak social roots has been forced to rely on the support of ‘warlords’ to stay in power. But a high price had to be paid.
Giustozzi, Antonio
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Eritrea's Nation and State-building: Re-assessing the impact of 'the struggle' [PDF]

open access: yes
In the April 2003 issue of Atlantic Monthly, Robert Kaplan describes Eritrea as 'newly independent, sleepily calm and remarkably stable'. Electricity is said to fail infrequently, corruption is rare, theft and crime almost unheard of, reflecting, Kaplan ...
Sara Rich Dorman
core  

In Pursuit of Hegemony: Politics and State Building in Sri Lanka [PDF]

open access: yes, 2013
Since the late colonial period, Sri Lanka has been subject to modern democratic state building experiments. The number of challenges this project has encountered is rising.
Jayasundara-Smits, S.M.S. (Shyamika)
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

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