Results 61 to 70 of about 1,149,335 (314)

Particle filter for state of charge and state of health estimation for lithium-iron phosphate batteries

, 2022
S.705-710The paper presents a new approach for state estimation of lithium-iron phosphate batteries. Lithium-iron phosphate/graphite batteries are very intricate in state of charge estimation since the open circuit voltage characteristic is flat and ...
Vetter, Matthias, Straub, S., Schwunk, Simon, Armbruster, Nils, Kehl, J.   +4 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

State of Charge Estimation for Lithium-Ion Batteries Using Simple Recurrent Units and Unscented Kalman Filter

Frontiers in Energy Research, 2022
Accurate estimation of the state of charge plays a very important role in ensuring the safe and effective operation of battery lithium-ion batteries and is one of the most important state parameters.
Zhaowei Zhang, Zhaowei Zhang, Xinghao Zhang, Xinghao Zhang, Zhiwei He, Zhiwei He, Chunxiang Zhu, Chunxiang Zhu, Wenlong Song, Mingyu Gao, Mingyu Gao, Yining Song   +11 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

State-of-Charge Estimation of Reconfigurable Supercapacitor

Journal of Physics: Conference Series
Abstract A large body of research has been done on state-of-charge (SOC) estimate of supercapacitors in the literature; most of the works have been on SOC estimation of individual supercapacitor units. Nonetheless, supercapacitors are usually linked to balancing circuits in real-world applications in order to remove inter-cell imbalances.
Boyu Li, Yueyue Ma, Ren Zhu, Heng Li
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Direct numerical simulation of forced flow dielectric EHD within charge injection atomizers [PDF]

, 2010
A charge injection atomizer functions by introducing electric charge discharged from a high voltage electrode into a dielectric liquid, which subsequently atomizes the ejected liquid jet.
Kourmatzis, Agissilaos, John Shrimpton, Shrimpton, J.S., Agissilaos Kourmatzis   +3 more
core   +1 more source