Results 191 to 200 of about 3,079,233 (343)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Estimation of state of health for lithium-ion batteries using advanced data-driven techniques. [PDF]

Sci Rep
Rout S, Samal SK, Gelmecha DJ, Mishra S.
europepmc   +1 more source

Der Arzt am Beginn des 21. Jahrhunderts: Zwischen Hippokrates und Staatsmedizin@@@The physician at the beginning of the twenty-first century: between Hippocrates and State medicine: Einbecker-Empfehlungen der Deutschen Gesellschaft für Medizinrecht (DGMR) e.V.@@@Einbecker recommendations of the German Society for Health Care Law

, 2008
Andreas Wienke
openalex   +1 more source

Corrigendum to “A method for estimating lithium-ion battery state of health based on physics-informed machine learning” [J. Power Sour. 627 (2025) 235767]

Guoqing Sun, Yafei Liu, Xuewen Liu
openalex   +1 more source

Estimation of the State of Charge/Health of Electric Vehicle Batteries Through Machine Learning Approach [PDF]

Capasso Clemente, Chianese Giovanni, Veneri Ottorino, Patalano Stanislao, Vitolo Ferdinando   +4 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Machine Learning-Assisted Prediction of State of Health in Lithium Metal Batteries with Electrochemical Impedance Spectroscopy. [PDF]

Small Sci
Yoon J, Chae S, Jeong C, Lee M, Jang S, Woo K, Cho H, Yang W.   +7 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

State-of-health indicators

Identification of generic stateofhealth indicators of fuel cell system and tank ...
openaire   +1 more source

STUDENT STATE OF HEALTH OF NIZHYN HIGHER SCHOOL (late 19th – 20s of the 20th century) [PDF]

Serhii KYRYLENKO, Oleksii LEIBEROV
openalex   +1 more source