Results 281 to 290 of about 3,079,233 (343)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Lithium-ion battery state of health and failure analysis with mixture weibull and equivalent circuit model. [PDF]

iScience
Hu W, Qian Q.
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

State of health estimation of LIB based on discharge section with multi-model combined. [PDF]

Heliyon
Xu P, Huang Y, Ran W, Wan S, Guo C, Su X, Yuan L, Dan Y.   +7 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Novel Insight into the Association between Balneotherapy and Functional State and Health Perception in Chronic Low Back Pain: A Cross-Sectional Study. [PDF]

J Clin Med
Terzic Markovic D, Kocic S, Bradic J, Jurisic-Skevin A, Jakovljevic B, Majstorovic B, Dimoski Z, Stojanovic G, Maksimovic V, Pavlovic Jugovic K, Dabic M, Jezdimirovic D, Zivanovic S.   +12 more
europepmc   +1 more source

State-Level Pro- and Anti-Transgender and Gender-Diverse (TGD) Legislation and Mental Health Among TGD Young Adults in the United States

Michael J. Pellicane, Tara Weixel, Jeffrey A. Ciesla   +2 more
openalex   +1 more source

Electrochemical Circuit Model Based State of Health Prognostics for Evaluation of Reusability of Lithium-Ion Batteries from Electric Vehicle. [PDF]

Molecules
Kang H, Oh M, Kim J, Shin E, Hwang K, Kim S, Chi Y, Park C, Yoon S.   +8 more
europepmc   +1 more source

Deep Learning-Based State-of-Health Estimation of Proton-Exchange Membrane Fuel Cells under Dynamic Operation Conditions. [PDF]

Sensors (Basel)
Zhang Y, Tang X, Xu S, Sun C.
europepmc   +1 more source