Results 221 to 230 of about 711,827 (305)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Immune exhaustion, the culprit for long COVID and chronic complications. [PDF]

J Leukoc Biol
Geng S, Li L.
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Building reparative futures demands a reckoning with the crisis form of global health. [PDF]

PLOS Glob Public Health
Sekalala S, Lake S.
europepmc   +1 more source

Annual Report of the Commissioner of State Aid and Pensions: For the Year 1917

, 1918
Massachusetts. Commissioner of State Aid and Pensions.
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

The 'vulnerability paradox': how institutional legacies shaped Colombia's response to Venezuelan displacement. [PDF]

Disasters
Fernández-Rodríguez N.
europepmc   +1 more source

Annual Report of the Commissioner of State Aid and Pensions: For the Year 1910

, 1911
Massachusetts. Commissioner of State Aid and Pensions.
core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Out-of-hospital emergency medical services in Poland: organization, challenges, and modern solutions. [PDF]

Front Public Health
Mitura KM, Celiński D, Miłowski T, Leszczyński PK, Snarska J, Gałązkowski R, Szajda SD.   +6 more
europepmc   +1 more source