Results 151 to 160 of about 1,932,765 (302)

South Carolina's dedication to education

open access: yes, 2020
State Superintendent of Education Molly Spearman convened AccelerateED, a task force of educators and administrators who represent all aspects of the K-12 public education system.
South Carolina State Department of Education
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Kansans can: 2015-2016 annual report, Kansas State Department of Education

open access: yes, 2017
"Jan. 18, 2017." Previous to 2015/16 this series was titled: Kansas State Board of Education Accountability ReportKansas State Board of Education -- KSDE leadership -- Vision -- Mission -- Motto -- Successful high school graduate -- Outcomes for ...
Kansas State Department of Education
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In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

OTHER TITLE: Launch: 2017-2018 annual report, Kansas State Department of Education

open access: yes, 2018
"Dec. 10, 2018."Kansas State Board of Education -- KSDE leadership -- [Introduction by Dr. Randy Watson, Kansas Commissioner of Education] -- Year in review -- Kansans can: School redesign project -- Social-emotional growth -- Kindergarten readiness ...
Kansas. State Department of Education.
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Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

OTHER TITLES: 2006-2007 Accountability Report: Education in Kansas. [Kansas State Board of Education Annual Report, 2006-2007]. Kansas State Department of Education Annual Report

open access: yes, 2007
"December 2007." "Kansas schools continue to demonstrate strong performance on all measures in 2006-2007. Achievement continues to be high, performance gaps are narrowing, and the state continues to do well when compared to the rest of the states on ...
Kansas. State Board of Education
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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

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