Results 41 to 50 of about 1,244,483 (233)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Teachers' Decision-Making about Place-Based Education and State Testing

open access: yesThe Rural Educator, 2018
This qualitative study examined the effects of a high-stakes, standardized test on teachers' instructional planning at a rural school. The research addressed this question: How do mandated curricular standards affect teachers' instructional planning and ...
Timothy G. Thomas
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Fertility and education in Poland during state socialism

open access: yesDemographic Research, 2014
Background: Studies on fertility in Poland focus on the turbulent transition period and its consequences. However, during state socialism significant societal and demographic changes took place.
Zuzanna Brzozowska
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Aesthetic and Formative values of Mural Painting Scenes in Ancient Egyptian Art As a Suggested Introduction to Appreciating Contemporary Wooden Murals

open access: yesJournal of Architecture, Art & Humanistic Science
The research deals with studying the aesthetic and plastic values of mural scenes in ancient Egyptian art and using them as a suggested entry point for appreciating contemporary wooden murals, by clarifying the importance of wall painting in general and ...
Dr. Dalia Mohamed Mahmoud Sharaf Lecturer of Art History and Appreciation, Department of Art Education, Faculty of Specific Education, Alexandria University   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Integrated and Inclusive Higher Education in Vladimir State University: Current State and Development Perspectives

open access: yesПсихологическая наука и образование, 2017
The paper summarizes the many years of experience in methodological support and training at the Center of Professional Education for the Disabled and at the “Inclusive Education” Research and Educational Center of the Vladimir State University.
Yegorov I.N., , Panfilov A.N.,
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Estado e políticas (públicas) sociais

open access: yesCadernos Cedes
Para melhor compreensão e avaliação das políticas públicas sociais implementadas por um governo, é fundamental a compreensão da concepção de Estado e de política social que sustentam tais ações e programas de intervenção.
ELOISA DE MATTOS HÖFLING
doaj   +1 more source

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