Results 151 to 160 of about 19,979 (260)

A municipality-level, monthly dataset of disappearance cases and outcomes in Mexico from the National Registry of Disappeared Persons, 2015-2025. [PDF]

Data Brief
Escobar MA, Reyes-Guzman G, Sanchez Ruiz A.   +2 more
europepmc   +1 more source

De Novo Designed Minibinders Targeting the GDF15–GFRAL Axis Reverse Cancer Cachexia and Restore Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang, Tianzhen Hua, Meiling Wang, Bingbing Meng, Yue Zhang, Chengxu Jiang, Yunhe Gao, Hongqi Yang, Jian Bo   +8 more
wiley   +1 more source

Effectiveness and Sustainability of Water Chlorination in Public Healthcare Services in Guatemala. [PDF]

Trop Med Infect Dis
Garzaro P, Castillo C, Fahsen N, Santos L, Lu J, Hug C, Lozier M, Call DR, Cordón-Rosales C, Ramay BM.   +9 more
europepmc   +1 more source

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

Advanced Science, EarlyView.
ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen, Haoyu You, Hefa Huang, Huihui Chai, Ruize Zhu, Yun Guan, Qisheng Tang, Tianwen Li, Shan Jiang, Houshi Xu, Peng Wang, Yue Wang, Maoyuan Sun, Beining Liu, Zhen Li, Yulai Zeng, Weiqiu Ping, Yanlin Teng, Songlin Yan, Qinghui Li, Long Gu, Tao Sun, Zhifeng Shi   +22 more
wiley   +1 more source

Cultural and Institutional Factors Driving Severe Repetitive Flood Losses: Insights From the Jersey Shore. [PDF]

Risk Anal
Geronimo L, Payne WB, Andrews CJ, Gilmore EA, Kopp RE.   +4 more
europepmc   +1 more source

Closed‐Loop Decoding and Intervention of Pain: A Novel BMI Strategy Integrating θ‐Band Detection and Mechano‐Electro‐Biological Coupled Hydrogels

Advanced Science, EarlyView.
A closed‐loop brain–machine interface with a PFAPT hydrogel electrode identifies prefrontal θ‐band as a neuropathic pain biomarker. The hydrogel enables stable 28 d ECoG recording and delivers θ‐triggered cortical stimulation, alleviating pain and affective behaviors in rats via bidirectional regulation of inflammation and central sensitization ...
Yun Ji, Tao Li, Guoqiang Lei, Huichun Luo, Xiuqian Guo, Jiao Xiang, Tao Shi, Weitang Liu, Yuxin Zhang, Xiaoyu Liao, Shutao Zhao, Jiayun Wu, Wangao Zhang, Wenhui Liu, Chuanglong He, Shuo Chen, Tao Wu, Ke Ma   +17 more
wiley   +1 more source

Comparative Analysis of Psychosocial Risks and Leadership in Municipal Government Agencies: A Study Based on NOM-035-STPS-2018 in Zacatecas, Mexico. [PDF]

Int J Environ Res Public Health
Villagrán Rueda S, Alvarado-Peña LJ, Vega Osuna LA, Salaiza Lizárraga FC, Ruvalcaba Sánchez MLG, Santos-Hernández BL, Muñóz Castorena RV, Martínez WFR.   +7 more
europepmc   +1 more source

IMPLEMENTATION OF THE CIVIL PROTECTION CONCEPT THROUGH THE MANAGEMENT, USE AND DISPOSITION OF THE STATE AND MUNICIPAL PROPERTY

Public Security and Public Order, 2022
openaire   +1 more source

Ovarian Cancer Diagnosis and Chemoresistance Prediction Model Based on cfRNA Molecular Signature

Advanced Science, EarlyView.
A deep learning model analyzes cfRNA profiles extracted from the blood of OVCA patients. This innovative approach distinguishes OVCA from healthy controls with high accuracy. Crucially, it reliably predicts patient response to chemotherapy (sensitive versus resistant subgroups).
Qinhao Guo, Yangyang Zhang, Yongcheng Jin, Siwei Deng, Yongqi Chen, Zheng Feng, Hao Wen, Liu Wang, Yilin Li, Fanghong Ou, Yong Shen, Haiming Li, Tianyao Zhou, Xingzhu Ju, Xiaohua Wu   +14 more
wiley   +1 more source

New Cementitious Materials: Advances, Challenges, and Future Perspectives. [PDF]

Materials (Basel)
Saberian M.
europepmc   +1 more source