Results 131 to 140 of about 1,814,994 (315)

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

open access: yesAdvanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong   +21 more
wiley   +1 more source

State Implementation of National Health Reform: Harnessing Federal Resources to Meet State Policy Goals [PDF]

open access: yes, 2010
Discusses state options for maximizing coverage and access to care; reforming the health insurance market; holding insurers accountable for high-quality, affordable coverage; restructuring healthcare delivery and financing; and cutting budget ...
Stan Dorn
core  

INB3P: A Multi‐Modal and Interpretable Co‐Attention Framework Integrating Property‐Aware Explanations and Memory‐Bank Contrastive Fusion for Blood–Brain Barrier Penetrating Peptide Discovery

open access: yesAdvanced Science, EarlyView.
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv   +11 more
wiley   +1 more source

FREE RADICAL MODIFICATION OF PROTEINS AND LIPID IN ATRIAL FIBRILLATION

open access: yesКубанский научный медицинский вестник, 2016
At 105 patients with paroxysmal and permanent form of atrial fibrillation against the background of coronary heart disease (CHD) and without CHD were studied concerning the levels of peroxidation products and protein-Lipid rows.
M. O. Philippova   +2 more
doaj  

Late Budgets [PDF]

open access: yes
The budget forms the legal basis of government spending. If a budget is not in place at the beginning of the fiscal year, planning as well as current spending are jeopardized and government shutdown may result.
Asger L. Andersen   +2 more
core  

Fabrication of High‐Density Multimodal Neural Probes Based on Heterogeneously Integrated CMOS

open access: yesAdvanced Science, EarlyView.
A chiplet‐based methodology democratizes active neural probe development on standard bulk CMOS services. This yields the first probe combining high‐density electrophysiology (416 electrodes) with calcium imaging (832 photodiodes) and complete on‐chip signal processing across 13 shanks.
Ju Hee Mun   +10 more
wiley   +1 more source

Saving for a rainy day? [PDF]

open access: yes
State finance ; Budget ...
Thomas A. Garrett
core  

Intensifying Impact: State Budget Cuts Deepen Pain for Ohio Communities [PDF]

open access: yes, 2012
Policy Matters Ohio looked at the size and scope of cuts in each county and in many municipalities. We talked with city and county administrators, local elected officials and residents.
Tim Krueger, Wendy Patton
core  

Physical Implementation of Optical Material‐Based Neural Networks Processing Enabled by Long‐Persistent Luminescence

open access: yesAdvanced Science, EarlyView.
This study reports on the physical implementation of optical material‐based neural processing using long‐persistent luminescence as memory‐retention and nonlinear optical material. The system performs optical‐domain preprocessing with opto‐electronic interfaces for stimulus delivery and readout, enabling real‐time demonstrations including Pong gameplay
Sangwon Wi, Yunsang Lee
wiley   +1 more source

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