Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Modelling and Multi-stage Design of Membrane Processes Applied to Carbon Capture in Coal-fired Power Plants [PDF]
According to recent predictions, energy generation from coal will continue to play a key role in the next decades. The UK 2008 Climate Change Act requires a reduction of 80% of greenhouse gases emissions by 2050, and carbon capture and storage will have ...
Bocciardo, Davide. +2 more
core +1 more source
Measuring Governance, Corruption and State Capture: How Firms and Bureaucrats Shape the Business Environment in Transition Economies [PDF]
Recent studies have focussed on the characteristics and policies of the state to explain the extent and causes of corruption, with little attention paid to the role played by firms.
Daniel Kaufmann +3 more
core +2 more sources
Capitalising On Criminality: A New Lusophone Route through Mozambique
Mozambique is becoming recognised as an emerging hub for cocaine trafficking, with links stretching back to Brazil. The arrest of a well-known associate of Brazil’s Primeiro Comando da Capital (PCC) suggests the emergence of a new ‘lusophone route ...
Sasha Jesperson, Martin Verrier
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Parliamentary and Local Elections in Serbia 2023
The December 2023 Serbian parliamentary and local elections unfolded against the tragicbackdrop of two mass shootings in May, triggering a public outcry and widespreadprotests that demanded increased security measures.
Pavlović, Dušan
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Application of Advanced Technologies for CO2 Capture from Industrial Sources [PDF]
The great majority of the research on CO2 capture worldwide is today devoted to the integration of new technologies in power plants, which are responsible for about 80% of the worldwide CO2 emission from large stationary sources.
Boavida, Dulce +20 more
core +1 more source
Corruption has been a prevalent phenomenon in South Africa for an extended period, but it was during the presidential reign of Jacob Zuma that corruption evolved into state capture.
Ugljesa Radulovic
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

