Results 111 to 120 of about 3,748,422 (364)
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Questions and areas of study that need to be persued in order to develope a Controlled Ecological Life Support System are posed. Research topics needing attention are grouped under various leadings: ecology, genetics, plant pathology, cybernetics ...
Rummel, J. D.
core +1 more source
Lexical Entries for Verbs [PDF]
, 1968 Sponsored in part by the National Science Foundation through Grant GN 534.1 from the Office of Science Information Service to the Computer and Information Science Research Center, The Ohio State ...
Fillmore, Charles J.
core
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Review of Componential Analysis of General Vocabulary: The Semantic Structure of a Set of Verbs in English, Hindi, and Japanese, Part II, Bendix, Edward Herman (I.J.A.L. Vol. 32, No. 2, Publication 41) 1966 [PDF]
, 1968 Sponsored in part by the National Science Foundation through Grant GN 534.1 from the Office of Science Information Service to the Computer and Information Science Research Center, The Ohio State ...
Fillmore, Charles J.
core
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
A Second Opinion on the Current State of Affairs in Computer Science Education: An Australian Perspective [PDF]
, 2006 Lakshmi Narasimhan
openalex +2 more sources
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
A new cross-platform architecture for epi-info software suite
BMC Bioinformatics, 2018 Background The Epi-Info software suite, built and maintained by the Centers for Disease Control and Prevention (CDC), is widely used by epidemiologists and public health researchers to collect and analyze public health data, especially in the event of ...
Blake Camp +6 more
doaj +1 more source