Results 111 to 120 of about 532,220 (309)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Learning objectives for courses in the Department of Computer Science, Oregon State University

open access: yes
This document describes the overall learning objectives for courses in the department of computer science at Oregon State ...
Oregon State University. Department of Computer Science
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Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Computer assisted instruction for computer science

open access: yes, 1986
Includes bibliographical references (pages 88-90)This paper surveys the state of the art of Computer\ud Assisted Instruction (CAI) in general and concentrates\ud on what has been developed for university level Computer\ud Science.
Lulovics, Georgia Demetry
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Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The state of science convergence in implantable brain-computer interface clinical trials

open access: yesJournal of Neural Engineering
Abstract Objective. Advances in implantable brain-computer interfaces (iBCI) have rapidly accelerated in the last decade that promises to improve the quality of life of patients with communications, sensory, and motor control disabilities. Approach.
K Michelle Patrick-Krueger   +2 more
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Modern trends in knowledge representation and expert system technology

open access: yesLe Matematiche, 1988
We will not be concerned with hardware aspects but we will discuss the present state of methodological concepts and software tools. Our main examples stem from the research activities at the Computer Science Department of the University of Kaiserslautern.
Klaus Nökel, Michael M. Richter
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Wright State University College of Engineering and Computer Science Bits and PCs newsletter, Volume 8, Number 6, September 1992

open access: yes, 1992
An eight page newsletter created by the Wright State University College of Engineering and Computer Science that addresses the current affairs of the college.https://corescholar.libraries.wright.edu/bits_pcs/1029/thumbnail ...
College of Engineering and Computer Science, Wright State University
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