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Wright State University College of Engineering and Computer Science Bits and PCs newsletter, Volume 9, Number 2, February 1993

open access: yes, 1993
A fourteen page newsletter created by the Wright State University College of Engineering and Computer Science that addresses the current affairs of the college.https://corescholar.libraries.wright.edu/bits_pcs/1033/thumbnail ...
College of Engineering and Computer Science, Wright State University
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Wright State University College of Engineering and Computer Science Bits and PCs newsletter, Volume 20, Number 1, September 2003

open access: yes, 2003
An eight page newsletter created by the Wright State University College of Engineering and Computer Science that addresses the current affairs of the college.https://corescholar.libraries.wright.edu/bits_pcs/1131/thumbnail ...
College of Engineering and Computer Science, Wright State University
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Wright State University College of Engineering and Computer Science Bits and PCs newsletter, Volume 21, Number 6, March 2005

open access: yes, 2005
An eight page newsletter created by the Wright State University College of Engineering and Computer Science that addresses the current affairs of the college.https://corescholar.libraries.wright.edu/bits_pcs/1144/thumbnail ...
College of Engineering and Computer Science, Wright State University
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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