Results 201 to 210 of about 3,053,358 (290)

Multi-task meta-initialized DQN for fast adaptation to unseen slicing tasks in O-RAN. [PDF]

PLoS One
Zeng B, Niu X.
europepmc   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Does provable absence of barren plateaus imply classical simulability? [PDF]

Nat Commun
Cerezo M, Larocca M, García-Martín D, Diaz NL, Braccia P, Fontana E, Rudolph MS, Bermejo P, Ijaz A, Thanasilp S, Anschuetz ER, Holmes Z.   +11 more
europepmc   +1 more source

Infusing Inclusion, Diversity, and Social Justice into the Undergraduate Computer Science Curriculum at Boise State University [PDF]

Donald J. Winiecki, Noah Salzman, Timothy D. Andersen, Amit Jain, Dianxiang Xu   +4 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Rapid Detection of Perfluorooctanesulfonic Acid Using Surface-Enhanced Raman Spectroscopy and Deep Learning. [PDF]

ACS Omega
Juhong A, Li B, Liu Y, Yao CY, Yang CW, Ullah AKMA, Huang X, Horprathum M, Piyawattanametha W, Li H, Qiu Z.   +10 more
europepmc   +1 more source

Geographical Inequities in Accessing Engineering and Computer Science: A State-wide Analysis of Undergraduate Enrollments Across High Schools [PDF]

David B. Knight, Jacob Grohs, Holly Matusovich, Isabel S. Bradburn, Cheryl Carrico, Kai Jun Chew, Michelle Klopfer   +6 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Study on quantum thermalization from thermal initial states in a superconducting quantum computer. [PDF]

Sci Rep
Edo ME, Wu LA.
europepmc   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source