Results 111 to 120 of about 270,952 (352)

Dysregulation of Oral Microbial Eicosapentaenoic Acid Induced by Chronic Restraint Stress Exacerbates Periodontitis via M1 Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo   +13 more
wiley   +1 more source

Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays

open access: yesAdvanced Science, EarlyView.
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen   +13 more
wiley   +1 more source

The Markers Of Bone Metabolism And System Inflammation In Patients With Osteoarthritis Depending On Body Mass, The Influence Of Symptomatic Slow Acting Drugs [PDF]

open access: yes, 2016
Aim. To assess the levels of markers of the bone synthesis and system inflammation in patients with osteoarthritis (OA) in combination with obesity and their dynamic under the influence of basic treatment.Materials and methods.
Cherkasova, A. (Anna)   +1 more
core  

Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity

open access: yesAdvanced Science, EarlyView.
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou   +8 more
wiley   +1 more source

Association of a Multimodal Perioperative Care Program With Postoperative Complications in Elderly Patients Undergoing Gastrectomy for Gastric Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Implementation of a multimodal perioperative care program and reduction of postoperative complications. ABSTRACT Purpose This retrospective study aimed to assess the clinical effectiveness of a multimodal perioperative care program in reducing postoperative complications in elderly patients undergoing gastrectomy for gastric cancer.
Keiichi Fujiya   +13 more
wiley   +1 more source

Relationships between spirituality and religiosity in dentistry academics in the state of Bahia [PDF]

open access: diamond, 2023
Ianderlei Andrade Souza   +3 more
openalex   +1 more source

Surgical Outcomes of Sequential Robot‐Assisted Hepatobiliary–Pancreatic Surgery in a Single Operating Room: A Single‐Center Retrospective Analysis of a High‐Volume Center in Japan (TAKUMI‐6)

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study investigated the surgical outcomes of sequential robot‐assisted hepatobiliary–pancreatic (HBP) in a single operating room. The outcomes and operating room timelines were comparable between the first and second cases. The median turnover time was 49 min, and the day‐shift completion success rate was 34.4%.
Tomokazu Fuji   +7 more
wiley   +1 more source

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