Results 141 to 150 of about 270,952 (352)

NUAK2 Inhibition Enhances Macromolecular Drug Delivery in a 3D Fibrotic Model of the Pancreatic Tumor Microenvironment

open access: yesAdvanced NanoBiomed Research, EarlyView.
Using a 3D cell culture model of the fibrotic barrier in pancreatic cancer, this work shows that inhibiting NUAK2 kinase in pancreatic stellate cells enhances macromolecular drug delivery. Mechanistically, NUAK2 inhibition disrupted actin stress fiber assembly to downregulate collagen I expression, thus enhancing macromolecular permeability.
Misaki Nakamura   +14 more
wiley   +1 more source

Strategies for Improving the Diversity of the Health Professions [PDF]

open access: yes, 2003
Evaluates programs and strategies that were designed to increase the number of underrepresented African Americans, Native Americans, and Latinos in the health professions in California.
Claudia Munoz   +5 more
core  

Multimaterial Triphasic Scaffold Replicates Enthesis Microenvironment to Modulate Early Cell Responses

open access: yesAdvanced NanoBiomed Research, EarlyView.
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo   +7 more
wiley   +1 more source

Expanding the Phenotype of TAB2‐Related Syndrome: The First Case With Cleft Palate and Insights Into Palatal Development

open access: yes
American Journal of Medical Genetics Part A, EarlyView.
Alberto De Rosa   +7 more
wiley   +1 more source

Current state and trajectory of artificial intelligence in dentistry: A review [PDF]

open access: hybrid
Richa Wadhawan   +7 more
openalex   +1 more source

In Search of Dental Care: Two Types of Dentist Shortages Limit Children's Access to Care [PDF]

open access: yes, 2013
Each year in the United States, tens of millions of children, disproportionately low-income, go without seeing a dentist.This lack of access to dental care is a complex problem fueled by a number of factors, with two different dentist shortages ...

core  

Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola

open access: yesThe Anatomical Record, EarlyView.
Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum   +3 more
wiley   +1 more source

Comparison of Triple Combination Oral Sedation Regimens for Pediatric Dental Treatment [PDF]

open access: yes, 2019
Purpose: Compare the efficacy of two benzodiazepines (diazepam or midazolam) in combination with meperidine and hydroxyzine for pediatric dental sedation.
Henderson, Brett H
core   +1 more source

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