Results 71 to 80 of about 18,707,162 (297)

Sliding Mode Output Regulation for a Boost Power Converter

open access: yesEnergies, 2019
This work deals with the novel application of the sliding mode (discontinuous) output regulation theory to a nonlinear electrical circuit, the so-called boost power converter.
Jorge Rivera   +2 more
doaj   +1 more source

Simultaneous stabilization via static output feedback and state feedback [PDF]

open access: yesIEEE Transactions on Automatic Control, 1999
Summary: The simultaneous stabilization problem is considered using the matrix inequality approach. Same necessary and sufficient conditions for simultaneous stabilizability of \(r\) strictly proper multi-input/multi-output (MIMO) plants via static output feedback and state feedback are obtained in the form of coupled ARI's.
Yong-Yan Cao, Youxian Sun, James Lam
openaire   +5 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Robust Control of Unknown Observable Nonlinear Systems Solved as a Zero-Sum Game

open access: yesIEEE Access, 2020
An optimal robust control solution for general nonlinear systems with unknown but observable dynamics is advanced here. The underlying Hamilton-Jacobi-Isaacs (HJI) equation of the corresponding zero-sum two-player game (ZS-TP-G) is learned using a Q ...
Mircea-Bogdan Radac, Timotei Lala
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Dynamic Sliding Mode Control of Spherical Bubble for Cavitation Suppression

open access: yesAxioms
Cavitation is a disadvantageous phenomenon that occurs when fluid pressure drops below its vapor pressure. Under these conditions, bubbles form in the fluid.
Ali Karami-Mollaee, Oscar Barambones
doaj   +1 more source

Optimal periodic output feedback control: a continuous-time approach [PDF]

open access: yes, 2007
: This paper addresses the problem of optimal static output feedback control of linear periodic systems. The proposed approach, which allows to deal with both stable and unstable open loop systems, relies on a continuous-time formulation of the control ...
VIGANO', LUCA   +8 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Incorporating user search behaviour into relevance feedback [PDF]

open access: yes, 2003
In this paper we present five user experiments on incorporating behavioural information into the relevance feedback process. In particular we concentrate on ranking terms for query expansion and selecting new terms to add to the user's query.
van Rijsbergen, C.J.   +6 more
core   +2 more sources

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