Results 101 to 110 of about 5,222,438 (374)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

PROBLEMS OF LEGAL REGULATION OF STATE FINANCIAL CONTROL IN THE RUSSIAN FEDERATION AND THE EU

Гуманитарные и юридические исследования, 2021
The article deals with the topical problem of forming the legal framework of financial control in the Russian Federation and European countries.
G. V. Stankevich, E. V. Kasevich
doaj  

State Financial Control and Peculiarities of its Implementation in State Corporations

Учёт. Анализ. Аудит, 2019
The control over the expenditure and the accumulation of budget funds by institutions with a significant share of state capital is an important aspect, since these institutions, on the one hand, receive financing from the budgets of the Russian ...
Viktoriya Vital’evna Romanovskaya
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

STATE FINANCIAL CONTROL: CONCEPTS AND CLASSIFICATION

Municipal economy of cities
The article emphasises that the conditions of the market economy and the development of Ukrainian society require a new conceptual approach to the creation and functioning of the system of state financial control. Additionally, the significant growth of financial abuses and violations necessitates a fundamental theoretical study and the determination ...
V. Verbytska, V. Yakushkina
openaire   +1 more source

State ownership - a residual role? [PDF]

The author reviews the state of thinking on the governance role of state ownership. He argues that a gradual transfer of operational control and financial claims over state assets remains the most desirable goal, but it needs to be paced to avoid ...
Perotti, Enrico
core  

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

The content and properties of state financial control in ensuring the economic security of the state

Економіка, управління та адміністрування
The study of the content and properties of state financial control is relevant in the context of public administration, since its modern definitions are often limited to an economic approach that does not reflect its complex nature. A broad understanding
Ya.Yu. Levytskyi
doaj   +1 more source

STATE FINANCIAL CONTROL IN TERMS OF DIGITALIZATION OF THE INSTITUTIONAL ENVIRONMENT

Baltic Journal of Economic Studies, 2019
The purpose of the study is to substantiate the benchmarks of digitization of the institutional environment of state financial control in Ukraine based on foreign experience.
S. Volosovych, Yurii Baraniuk
semanticscholar   +1 more source