Results 71 to 80 of about 28,560,524 (295)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
DIRECTIONS FOR IMPROVEMENT OF STATE FINANCIAL CONTROL IN UKRAINE
Baltic Journal of Economic Studies, 2016 The purpose of the paper is to offer the ways of development of the system of state financial control in Ukraine. The object of this research is the process of state financial control. Methodology.
Nataliia Miedviedkova
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The Concept of Financial Control of Communes Based on the Experience of Poland
Studia Ekonomiczne i Regionalne, 2021 Subject and purpose of work: The subject of the study are the elements of the Ukrainian financial control system. A combination of those elements enables formulating a concept which is directed at financial control of communes.
Belia Andriana, Storonyanska Iryna
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
MONITORING AS A FORM OF STATE FINANCIAL CONTROL
Гуманитарные и юридические исследования, 2021 The article attempts to explore the category of «monitoring» as a form of state financial control. Currently, the state financial control is undergoing a new legislative and subordinate regulation connected with introduction of new forms in practice. The
D. A. Smirnov, V. A. Melnikova
doaj
State Financial Control and Peculiarities of its Implementation in State Corporations
Учёт. Анализ. Аудит, 2019 The control over the expenditure and the accumulation of budget funds by institutions with a significant share of state capital is an important aspect, since these institutions, on the one hand, receive financing from the budgets of the Russian ...
Viktoriya Vital’evna Romanovskaya
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
STATE FINANCIAL AUDIT AS A TYPE OF FINANCIAL CONTROL
Karelian Scientific Journal, 2022 Daria Alexandrovna LAVROVA +1 more
openaire +1 more source