Results 81 to 90 of about 28,560,524 (295)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
State Auditor's report June 30, 2018 [PDF]
, 2018 The Office of State Auditor audited the financial statements of the South Carolina Office of the Governor, Executive Control of State using agreed upon ...
South Carolina State Auditor +1 more
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Legal regulation of state (municipal) financial control
Russian Journal of Economics and Law, 2014 Objective: to research the novels of budget and administrative legislation in the sphere of state (municipal) financial control, which allows to increase the quality of state financial management.
L. M. Faizrakhmanova
doaj
Priority aspects of the development of the system of state financial control in Ukraine
Публічне управління та регіональний розвиток, 2018 Effective state financial control is the most important condition for the existence of a strong state and an important factor in state-building. Therefore, the creation of a clear system of public financial control, the determination of the place and ...
Volodymyr Yemelyanov, Dmytro Stepaniuk
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Agency budget plan SC State Board of Financial Institutions Fiscal Year 2014-15
, 2014 The South Carolina Board of Financial Institutions submitted to the South Carolina Budget and Control Board, Office of State Budget an annual budget plan with summary of agency's request, program revision request, capital or non-recurring requests, and ...
South Carolina Budget and Control Board, Office of State Budget
core +1 more source
Principles of state financial control in the state defense order fulfillment
Ученые записки Казанского университета: Серия Гуманитарные наукиIn times of geopolitical tensions and hostile political conditions, any state prioritizes defense capability programs and projects, including those in the fulfillment of the state defense order, to protect its independence and sovereignty.
R. P. Shirenin
doaj +1 more source
Drug provision and health technology assessment in France
Фармакоэкономика, 2020 The article presents the description of structural, organizational and methodological issues of health technology assessment (HTA) of French drugs as well as the state-reimbursable list of drugs.
V. V. Omelyanovskiy +3 more
doaj +1 more source