Results 61 to 70 of about 2,305,611 (316)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Method for Determining the Risk Profile of Investors Based on the Relationship of Two Stock Investing Problems

Финансы: теория и практика
The subject of research in this paper is the investor’s risk profile as a characteristic of his behavior in the stock market.   The purpose of the study is to assess the investor’s risk profile in the form of a risk ratio in a model with a linear ...
V. A. Gorelik, T. V. Zolotova
doaj   +1 more source

The Prospects and Reform of the System of Control over the Efficiency of Use of Budget Funds in Ukraine [PDF]

Bìznes Inform, 2020
The article is aimed at studying the prospects and reform of the system of control over the efficiency of use of budget funds in Ukraine. It is determined that the State financial control is the regulated by the financial legal norms activities of the ...
Kuranda Liudmyla O., Liganenko Iryna V.
doaj   +1 more source

FEATURES OF THE FUNCTIONING OF STATE FINANCIAL CONTROL BODIES

, 2021
The relevance of studying the features of the functioning of external state financial control bodies and its features in our modern state is beyond doubt, since among the types of state financial control, this type is a priority in terms of monitoring the internal procedure for bringing public finances to users, as well as in general for compliance ...
SHEPELEVA, DINA, TOCHILIN, IGOR
openaire   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

The concept of internal financial control in a State-financed institution [PDF]

International Accounting, 2021
Subject. The article discusses the definition of Internal Financial Control in a State-Financed Institution and relevant issues. Objectives. I determine the substance of internal financial control with respect to operations of a State-financed institution. Methods. The study is based on methods of analysis, grouping, comparison, generalization, and the
openaire   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, Volume 19, Issue 7, Page 1918-1934, July 2025.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, Volume 19, Issue 7, Page 1897-1917, July 2025.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Organization and financial support of healthcare for public employees in the Russian Federation: a review of departmental health services in the Ministry of Defense

Фармакоэкономика, 2019
The review outlines the main legislative aspects of organization and financial support of health services for public institution employees inRussia. Specifically, the review describes the legal framework and regulations of healthcare for servicepersons ...
D. V. Lukyantseva, L. S. Melnikova, D. V. Fedyaev, T. P. Bezdenezhnykh, V. V. Omelyanovskiy   +4 more
doaj   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, Volume 19, Issue 7, Page 2144-2153, July 2025.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source