Results 91 to 100 of about 1,418,610 (267)

A new approach to investigate arthropod biodiversity in forest ecosystems, using meta‐barcoding on trap combinations

Ecological Solutions and Evidence
Autonomous monitoring of arthropod biodiversity is regularly based on a single trap type. However, the taxonomic composition of samples strongly depends on the trap type, and even the most widely used systems catch very different subsets of species from ...
Stephan Kühbandner, Jérôme Morinière, Markus Blaschke, Jörg Müller   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Spatial transcriptomics uncovers vasculature-centered cellular interactions driving Japanese encephalitis progression in a mouse model

Nature Communications
The cellular interactions that drive the neuropathology of most neuroinvasive viruses remain elusive. We used Japanese encephalitis virus (JEV) to infect female BALB/c mice and applied Stereo-seq to simultaneously capture host and viral transcriptomes in
Zhihua Ou, Zhaoyang Wang, Qi Chen, Peidi Ren, Xiuju He, Yan Liang, Ying’an Liang, Jiaxuan Wang, Sha Liao, Dexin Wang, Jie Zhao, Oujia Zhang, Zhenyu Peng, Jianxin Su, Wangsheng Li, Guohai Hu, Ao Chen, Ziqing Deng, Xin Jin, Xun Xu, Junhua Li, Gong Cheng   +21 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Identification of excited states in $^{226}$U

, 1999
Two experiments have been performed at the Accelerator Laboratory of the Department of Physics, University of Jyväskylä, Finland, and are reported here. The first experiment was a recoil-decay tagging study intended to delineate the level scheme of 226U for the first time.
Greenlees, P.T., Amzal, N., Butler, P.A., Cann, K.J., Cocks, J.F.C., Howcroft, D., Jones, G.D., Page, R.D., Andreev, A., Enqvist, T., Fallon, P., Gall, B.J.P., Guttormsen, M., Helariuttab, K., Hessberger, F.P., Hoellinger, F., Jones, P., Julin, R., Juutinen, S., Kankaanpaa, H., Kettunen, H., Kuusiniemi, P., Leino, M., Messelt, S., Muikku, M., Savelius, A., Schiller, A., Siem, S., Trzaska, W.H., Tveter, T., Usitalo, J.   +30 more
openaire   +2 more sources

Forensic short tandem repeat markers alteration in cancerous tissues: a scoping review

Egyptian Journal of Forensic Sciences
Background Short Tandem Repeats (STRs) are segments of DNA composed of a short sequence of nucleotides that repeat consecutively. These repeating sequences exhibit distinct lengths and nucleotide sequences among individuals, showcasing high variability ...
Izzah Syahira Omar, Md Yusop Nur Hafiza, Zainuddin Zafarina, Mohd Nafi Siti Norasikin, Mohd Isa Seoparjoo Azmel, Mohamed Yusoff Shafini, Hanis Z. A. NurWaliyuddin   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Tool Wear State Identification Based on SVM Optimized by the Improved Northern Goshawk Optimization. [PDF]

Sensors (Basel), 2023
Wang J, Xiang Z, Cheng X, Zhou J, Li W.
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source