Results 61 to 70 of about 638,308 (266)

Conceptual Sphere of Media Discourse of Maternity in Russian and Danish Print Mass Media

open access: yesВестник Волгоградского государственного университета: Серия 2. Языкознание, 2018
The results of linguoculturological analysis of the Russian and the Danish web-based media texts are described in the paper. The cultural and linguistic specifics of the representation of conceptual sphere of maternity media discourse – a fragment of the
Anna A. Kuvychko   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

About status and role of the Russian language in Republic of Armenia

open access: yesPolylinguality and Transcultural Practices, 2010
Nowadays in republic of Armenia are going on disputes on Russian language status. Russian is an integral part of the Armenian culture as long as republic of Armenia was a part of the USSR.
K A Bogdanova
doaj  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Language Policy of Ukraine: Post-colonial Traditions and Anti-colonial Tendencies

open access: yesФілологічні студії
The article describes common features of the colonial impact of Russia in the form of empire and the Soviet Union on the language policy of Ukraine, specifics of anti-colonial resistance and post-colonial manifestations caused by the deliberate ...
Olena Dotsenko
doaj   +1 more source

ON FORENSIC LINGUISTS AND NON-EXPERTS INTERPRETATION OF MULTIMODAL TEXTS

open access: yesВестник Волгоградского государственного университета: Серия 2. Языкознание, 2020
The article presents intermediate results of an experimental research into psycholinguistic characteristics of understanding multimodal texts with extremist content.
Aleksandra V. Gorbacheva   +2 more
doaj   +1 more source

Regular language quantum states

open access: yesQuantum
We introduce regular language states, a family of quantum many-body states. They are built from a special class of formal languages, called regular, which has been thoroughly studied in the field of computer science. They can be understood as the superposition of all the words in a regular language and encompass physically relevant states such as the ...
Marta Florido-Llinàs   +3 more
openaire   +3 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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