Results 141 to 150 of about 15,076,620 (365)
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
RESTRICTION OF TUBERCULOSIS.Read in the Section on State Medicine, at the Forty-fifth Annual Meeting of the American Medical Association held at San Francisco, June 5-8, 1894. [PDF]
J. H. Davisson
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Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
The worrying, current state of addictions training in medicine
Robert M. Lundin+4 more
doaj +1 more source
PREVENTION OF DIPHTHERIA FROM THE STANDPOINT OF THE HEALTH OFFICER.Read in the Section on State Medicine, at the Forty-fifth Annual Meeting of the American Medical Association, held at San Francisco, June 5-8, 1894. [PDF]
U. O. B. Wingate
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Precision Medicine in Africa: Current State and Strategies for development
Precision medicine is a transformative approach in modern healthcare that tailors medical treatments based on an individual’s genetic profile, environmental factors, and lifestyle choices.
Patrick Ashinze+9 more
doaj +1 more source