Results 71 to 80 of about 15,076,620 (365)

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

open access: yesFEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling   +4 more
wiley   +1 more source

Diabetes ROADMAP: Teaching Guideline Use, Communication, and Documentation When Delivering the Diagnosis of Diabetes

open access: yesMedEdPORTAL, 2020
Introduction Most interventions to date regarding breaking bad news focus on late-stage disease or disclosing a cancer diagnosis. Little attention has been given to delivery of chronic metabolic disease diagnoses such as prediabetes/type 2 diabetes ...
Christy J. W. Ledford   +10 more
doaj   +1 more source

Assessment of Knowledge, Attitude, and Utilization of Traditional Medicine among the Communities of Debre Tabor Town, Amhara Regional State, North Central Ethiopia: A Cross-Sectional Study

open access: yesEvidence-Based Complementary and Alternative Medicine, 2020
Background Traditional medicine is used by about 80% of the Ethiopian people to meet their healthcare needs. The aim of this study was to assess the knowledge, attitude, and practice of the community on traditional medicine in Debre Tabor town. Methods A
Tezera Jemere Aragaw   +2 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Department of Family Medicine 2005 Annual Report [PDF]

open access: yes, 2006
2005 annual report includes: WSU Trains Family Medicine Physicians; Letter from the Chair, Maryjean Schenk; Introducing New Faculty; Full-time affiliate and voluntary faculty; In memoriam of Bernard Dash; Faculty Serving in the Dean\u27s office; Faculty ...
Wayne State University School of Medicine, Department of Family Medicine and Public Health Sciences
core   +1 more source

Mathematical and Statistical Techniques for Systems Medicine: The Wnt Signaling Pathway as a Case Study

open access: yes, 2015
The last decade has seen an explosion in models that describe phenomena in systems medicine. Such models are especially useful for studying signaling pathways, such as the Wnt pathway.
A Gelman   +73 more
core   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Thoughts on the state of family medicine in South Africa

open access: yesSouth African Family Practice, 2013
No abstract available.
I. Couper, S. Fehrsen, J. Hugo
doaj   +3 more sources

Current State of Precision Medicine in Primary Systemic Vasculitides

open access: yesFrontiers in Immunology, 2019
Precision medicine (PM) is an emerging data-driven health care approach that integrates phenotypic, genomic, epigenetic, and environmental factors unique to an individual.
Erkan Demirkaya   +5 more
doaj   +1 more source

Obstacles and Challenges to Implementing Multi-departmental QI at a Large, Academic Training Center-Lessons Learned from a HCV Screening Program [PDF]

open access: yes, 2017
Objectives: We aimed to double the HCV screening rate of ‘baby-boomers’ admitted to the medicine teaching service at Methodist Hospital over the course of 6 months and demonstrate improved linkage to care for HCV RNA+ individuals. Initial efforts were a
Arastu, MD, S.   +6 more
core   +1 more source

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