Results 31 to 40 of about 5,071,375 (230)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

VARIOUS HISTORICAL CONNOTATIONS OF THE CONCEPT OF SOVEREIGNTY [PDF]

open access: yesChallenges of the Knowledge Society, 2018
Sovereignty as a feature of state power, shall be expressed in terms of organizing and exercising, determining and resolving internal and external problems, freely and according to its will, without any interference, respecting the sovereignty of other
Emilian CIONGARU
doaj  

The rule of law in response to the COVID-19 emergency: a comparative analysis

open access: yesRevista Catalana de Dret Públic, 2023
This work presents an analysis of the measures adopted by leading democratic countries in response to the COVID-19 emergency, and the compatibility issues that arose between these measures and the guarantees of the rule of law.
Carlos Garrido López
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Russia after the elections: strategy of breakthrough and anxieties of citizens

open access: yesНаука. Культура. Общество, 2019
The Russian government, focused on problems in foreign policy, carries out unpopular reforms among civil society, worsening, in the opinion of Russians, their socio-economic position in Russian society.
Victor K. Levashov   +3 more
doaj  

International standards and doctrinal understanding of legal authority as the basis for the formation of the democratic Ukrainian state

open access: yesНауково-інформаційний вісник Івано-Франківського університету права імені Короля Данила Галицького
Purpose. The article analyzes the legal nature and content of the rule of law as a principle, as well as the legal phenomenon and conceptual approach to the development of the modern Ukrainian State.
Kelbya S.
doaj   +1 more source

Regarding ensuring reliability of information by state information systems

open access: yesНауково-інформаційний вісник Івано-Франківського університету права імені Короля Данила Галицького, 2023
Purpose. The purpose of the study is to develop theoretical provisions on ensuring the reliability of information by state information systems. Method. The methodology includes a comprehensive analysis and generalization of the available scientific and ...
Lesko N.
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Algunas notas de una relectura de V. E. Orlando y Santi Romano sobre la personalidad jurídica del Estado

open access: yesRevista Vasca de Administración Pública, 2014
This work contains some selected notes from a reinterpretation of the main writings of Vittorio Emanuele Orlando and Santi Romano regarding the state legal personality and in general their conception of the relationships between Law and State.
José Luis Carro Fernández-Valmayor
doaj   +1 more source

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