Results 51 to 60 of about 1,398,157 (281)
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti +19 more
wiley +1 more source
Immune responses require delicate controls to maintain homeostasis while executing effective defense. Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor.
Aditi Kulkarni +6 more
doaj +1 more source
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner +14 more
wiley +1 more source
A Comprehensive Analysis on the Healthcare Systems in Latin America [PDF]
This comprehensive report summarizes and analyzes the current state of healthcare in Latin America, specifically in the countries of Mexico, Brazil, the Northern Triangle (El Salvador, Guatemala, and Honduras), the Andean Region (Ecuador, Peru, and ...
Calderon, Melinda +5 more
core +1 more source
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo +19 more
wiley +1 more source
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu +109 more
wiley +1 more source
Machado-Joseph Disease, A Case Report of Treatment Based on Phototherapy
Machado-Joseph disease (MJD) is a rare autosomal dominant disease caused by a mutation in exon 10 of the ATXN3 gene resulting from a cytosine-adenine-guanine trinucleotide repeat. A case of a 48-year-old man with MJD is reported. His father, two paternal
Hugo Mendieta Zerón +3 more
doaj +1 more source
This meta-analysis aims to identify if there are differences between the weight of lamb carcases and their main characteristics according to the production systems and type of feeding around the word. Lambs finished on feeding supplement (with or without
Lizbeth Esmeralda Robles Jiménez +5 more
doaj +1 more source
AUTOIMMUNE POLYGLANDULAR SYNDROME PREVALENCE IN TOLUCA, MEXICO
Objective: Autoimmune polyglandular syndromes (APS) are endocrinopathies whose main characteristic is the loss of immune tolerance. The objective of this work was to report the APS prevalence in an Internal Medicine Service from Toluca, Mexico ...
CONCEPCIÓN CARRILLO LE +4 more
doaj +1 more source
Evidence: Admission of Mathematical Probability Statistics Held Erroneous for Want of Demonstration of Validity [PDF]
In State v. Sneed the New Mexico Supreme Court limited its disapproval of evidence of probability statistics to the particular facts presented but failed to articulate specific safeguards for subsequent use of such evidence. This note explores the nature
core +1 more source

