Results 221 to 230 of about 171,965,011 (299)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Magnetic character of the low-energy enhancement in ⁷⁰Zn. [PDF]

Nature
Ronning EK, Richard AL, Liddick SN, Spyrou A, Ringle R, Arora H, Berg HC, Berkman JM, Bleuel DL, Bosmpotinis K, Campbell SE, Chen X, Crider BP, Coleman RJ, DeYoung PA, Doetsch AA, Erington H, Gaballah T, Gamage ND, Good EC, Greaves B, Hartley AC, Huffman J, Ireland CM, Izzo C, Jain R, Larsen AC, Larsson JEL, Lubna RS, Maier FM, Mogannam MJ, Mücher D, Mumpower MR, Owens-Fryar G, Ogunbeku TH, Scriven DP, Smith MK, Sumithrarachchi CS, Sweet A, Taft K, Tsantiri A, Uthayakumaar S, Wiedeking M.   +42 more
europepmc   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Humanistic thought in medical dao: a cross-cultural perspective of global medical humanities. [PDF]

Philos Ethics Humanit Med
Li Y, Cheng Y.
europepmc   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Quantum state-to-state reaction dynamics of F + HD → HF + D via a single partial wave shape resonance state. [PDF]

Nat Commun
Yuan D, Huang J, Li S, Chen W, Luo C, Tan Y, Lu Z, Shu Y, Zhang Y, Wang T, Fu B, Wang X, Zhang DH, Yang X.   +13 more
europepmc   +1 more source

Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier, Françoise Heran, Francis Lallemand, Pierre Bourdillon   +3 more
wiley   +1 more source

Selective filtering of multi-photon events from a single-photon emitter. [PDF]

Nat Commun
Sbresny F, Calcagno C, Kim SK, Boos K, Rauhaus W, Bopp F, Riedl H, Finley JJ, Zubizarreta Casalengua E, Müller K.   +9 more
europepmc   +1 more source

Author Correction: Organocatalytic enantioselective [2π + 2σ] cycloaddition reactions of bicyclo[1.1.0]butanes with α,β-unsaturated aldehydes

Nature Communications
Yi-Xiang Geng, Teng-Fei Xiao, Dong Xie, Ming-Ming Li, Pan-Pan Zhou, Guo-Qiang Xu, Peng-Fei Xu   +6 more
doaj   +1 more source

Author Correction: Flash upcycling of spent LiCoO₂ into oxygen-suppressed lithium-replenishing agent for high-performance batteries. [PDF]

Nat Commun
Liu G, Nie Q, Wan W, Yang F, Yang Z, Qu G, Guo L, Chen J, Wei X, Huang Y, Wang C.   +10 more
europepmc   +1 more source