Results 51 to 60 of about 171,965,011 (299)

Recommendations to unify phenological observations in Russia

open access: yesNature Conservation Research: Заповедная наука, 2020
In Russia, the methodics of phenological observation processing have been developing during many years. This aimed to unify the names of phenological phases and phenomena, uniform the signs of the onset of a particular phenological event. However, it was
Alexander A. Minin   +12 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Estimation of taxa included in the first volume of the Red Data Book of the Republic of Mordovia (Russia) using the IUCN Red List Categories and Criteria

open access: yesNature Conservation Research: Заповедная наука, 2017
The paper presents an estimation of taxa included in the first volume of the Red Data Book of the Republic of Mordovia using the IUCN Red List Categories and Criteria.
Anatoliy A. Khapugin   +7 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

LSTA fiscal year ... state program report overview

open access: yes, 2004
Annual; Electronic coverage as of Jan. 24, 2003: 1999-; Description based on: 1999; title from title screen (viewed 1/24/2003).; As part of the Library Services and Technology Act (LSTA) annual report which the State Library submitted to the Institute of
State Library of Ohio
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Report of the State Irrigation Commissioner to the Kansas State Board of Agriculture, 1922-24

open access: yes, 1924
WATER COMMISSION, KANSAS -- “The Kansas Water Commission was created by an Act of Legislature in 1917 for the purpose of investigating and controlling the problems of flood prevention, drainage, domestic water supply, water power, navigation and ...
Kansas. State Irrigation Commissioner
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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