Results 91 to 100 of about 170,677 (316)
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Legal analysis of the impact of Ghana s International Investment Agreements on the state's regulatory autonomy [PDF]
Commentators suggest Antonio meant that by virtue of all that had led up to that moment, the past had set the stage for their next act, as a prologue does in a play, and that the script is henceforth in their hands1.
Shang-Simpson, E.
core
Autonomy and Paternalism in Communitarian Society: Patient Rights in Israel
The Israeli Patient Rights Act attempts to accommodate personal autonomy within an avowedly paternalist communitarian state. Although Israel is still groping toward a solution, the legislation begins to show the different form a communitarian version of
Gross, Michael L.
core +1 more source
Considerations on University Teacher Autonomy
With reference to Kant, autonomy is defined as “the courage to use your mind”. As to teacher autonomy, it is examined in terms of the freedom of research and teaching.
P K Grechko
doaj
Este artigo resulta de Estado da Arte que sistematizou a produção científica em torno do tema da gestão, da autonomia e do funcionamento de órgãos colegiados em escolas da educação básica, entre 2000 e 2008.
Angela Maria Nartins +1 more
doaj +1 more source
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
A clash of traditions? An investigation into judicial interpretations of autonomy in ethically-contentious medical cases [PDF]
The concept of autonomy has acquired paramount status in English medical law, medical ethics and philosophy. Using the methodology of grounded theory, and three iterative cycles of enquiry of the medical law reports and the literature, this thesis ...
Bratton, M. Q. (Mark Q.)
core
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub +24 more
wiley +1 more source
Autonomy and Performance of Foreign Subsidiaries in five Transition Countries [PDF]
The paper analyses the link between the autonomy according to business function and the performance of foreign subsidiaries in Slovenia, Poland, Hungary, Slovakia and Estonia.
Urmas Varblane +2 more
core
Adaptive backstepping control for optimal descent with embedded autonomy [PDF]
Using Lyapunov stability theory, an adaptive backstepping controller is presented in this paper for optimal descent tracking. Unlike the traditional approach, the proposed control law can cope with input saturation and failure which enables the embedded ...
Macdonald, Malcolm +8 more
core +1 more source

