Results 41 to 50 of about 35,166 (233)

Ashwagandha: Is It Safe? Part 1: A Regulatory Review

Phytotherapy Research, EarlyView.
ABSTRACT Over the last decade, ashwagandha (Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler, R. Al‐Mondhiry, L. Lang, R. Marles, M. Tallon, A. Raghu   +5 more
wiley   +1 more source

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

Phytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou, Jingyun Chi, Yuan Ding, Zhidi Zhang, Rui Liang, Tianhao Wang, Yan Jiang, Rujun Song, Huazhou Fu, Xizhen Zhou   +9 more
wiley   +1 more source

The standartization of medicinal plant raw materials containing iridoids

Сеченовский вестник, 2011
Paper Standardization of herbal drugs, containing iridoids (review) describes comparative analysis of methods, used for Tests (TLC, macrochemical reactions) and Assay of herbal drugs in main Pharmacopoeias (U.S.
V. N. Kuzina, E. A. Malashenko, K. I. Eller   +2 more
doaj  

Medicinal plants of the Chinese Pharmacopoeia and Daodi: insights from phylogeny and biogeography [PDF]

, 2018
The Chinese Pharmacopoeia 2015 includes 584 plant medicines, of which 284 also contain high quality subsets, so called ‘Daodi’ components, where Daodi denotes superior clinical properties compared to non-Daodi counterparts despite being sourced from the ...
Al-Adhroey, Balick, Beckwith, Bennett, Bertea, Browner, Fu, Gorji, Heinrich, Hu, Hu, Huang, Huang, Jamal, Kala, Kishore, Leon, Leonti, Letunic, Meng, Moerman, Moerman, Ouarghidi, Pan, Qian, Qian, Revell, Saslis-Lagoudakis, Saslis-Lagoudakis, Saslis-Lagoudakis, Shrestha, Sivasankari, Stein, Tan, Tan, Uniyal, van Andel, Weber, Xing, Xue, Zhang, Zhao   +41 more
core   +1 more source

Extrahepatic Gene Editing In Vivo Using Organic Solvent‐Free Lipid Nanoparticles

Small, EarlyView.
This article highlights a novel, organic solvent‐free lipid nanoparticle (LNP) formulation that avoids cholesterol, thereby reducing hepatic accumulation and immune activation. These BLNPs enable potent, flexible, and scalable gene delivery, supporting personalized medicine and diverse nucleic acid applications.
Michael Streiber, Na Liu, Laurianne Simon, Franziska Adermann, Vivien Bachmann, Lucas Gath, Stephanie Hoeppener, Stephanie Schubert, Oliver Werz, Vincent Lapinte, Marie Morille, Michael Bauer, Adrian T. Press, Ulrich S. Schubert, Anja Traeger   +14 more
wiley   +1 more source

Influence of extraction methods on the composition of essential oils of Achillea millefolium L. from Lithuania [PDF]

, 2014
In this study, flowering aerial parts of Achillea millefolium were used as a matrix for supercritical CO2 extraction (SFE) of volatile oil. The collected extracts were analyzed by GC-FID and GC-MS methods and their composition were compared with that of ...
Bagdonaite, E., Falconieri, D, Marzouki, H, PIRAS, ALESSANDRA, PORCEDDA, SILVIA   +4 more
core   +1 more source

Pseudorandomised controlled trial of a novel navel barrier solution versus 10% iodine to protect navel and ear tag sites of neonatal lambs

Veterinary Record, EarlyView.
Abstract Background During lambing, 10% iodine is often used to protect neonatal navel and ear tag sites. The evidence for its effectiveness is sparse. Recently, a specific navel barrier solution (NBS) was developed. Here, an in vivo field trial compared the two treatments. Methods Ten farms reported data from 6840 lambs. The navel and ear tag sites of
Fiona M. Lovatt, Jonathan J. Powell, Carlos A. P. Bastos, Ian S. McCrone   +3 more
wiley   +1 more source

New Insights into Cannabis Consumption; Abuses and Possible Therapeutic Effects [PDF]

, 2015
Cannabis is one of the oldest psychotropic drugs known to humanity. The paper assesses the current knowledge on the cannabis, including the mechanisms of action and the therapeutic potential of cannabinoids.
Baconi, Daniela Luiza, Bălălău, Cristian, Vasile, Robert Daniel   +2 more
core   +3 more sources

Five‐Grass‐Pollen Sublingual Immunotherapy Drops Are Efficacious and Well Tolerated in Adults: The RHAPSODY Phase III Trial

Allergy, EarlyView.
The RHAPSODY multinational study investigated 26 months of continuous treatment with 5‐grass‐pollen sublingual SLIT drops in adults with moderate‐to‐severe grass‐pollen‐induced allergic rhinoconjunctivitis. The primary efficacy endpoint (the average daily total combined score) showed statistically significant differences in favour of the active ...
Alain Didier, Ruta Gronskyte Juhl, Terrie Dalgaard, Antoine Chartier, Philippe Devillier   +4 more
wiley   +1 more source

The development of the monographs for compoundED preparations for the state pharmacopoeia of Ukraine

Регуляторные исследования и экспертиза лекарственных средств, 2018
At present, there are certain topical issues related to the development of the standards for preparation and quality control of compounded medicines, the elaboration of quality assurance system for compounded preparations under the state policy ...
A. A. Zdoryk, L. P. Savchenko, V. A. Georgiyants, A. I. Gryzodub   +3 more
doaj