Results 101 to 110 of about 25,475,738 (290)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Predictable patterns of unpredictability: a literature review of discretion in migration control

Political Research Exchange
Migration control policies are marked by contradictory policy goals set in a complex web of intersecting international, national, and local regulations. This grants significant discretion to frontline workers. Despite the extensive research undertaken on
Lisa Marie Borrelli, Livia Johannesson, Annika Lindberg   +2 more
doaj   +1 more source

Report of State Electrician and Engineer to the General Assembly of the State of South Carolina [PDF]

, 1931
This report from the South Carolina State Electrician and Engineer’s Office to the General Assembly provides statistics on electric power consumption consumed by state institutions and cost, financial statement, sales of electricity, and expenditures for
South Carolina State Electrician and Engineer’s Office
core  

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

FEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

Deviant State: Domestic and Foreign Practices

RUDN Journal of Law
The task is to explore the optimal, healthy statehood for society and all its social strata. The focus lies on people’s standard of living, the protection of citizens’ rights and freedoms, and the prospects for their development.
Nikolai A. Vlasenko
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Siyasal Ekoloji Çerçevesinde Devlet Kudretinin Yeşilleşmesine İlişkin Bir Tartışma

Türk-Alman Üniversitesi Hukuk Fakültesi Dergisi
Bu çalışma kapsamında siyasal ekolojinin ideolojik temellerinden hareketle modern devlet iktidarının (Levitahan’ın) yeşilleşmesi incelenmiştir. Bu doğrultuda ekolojizm çerçevesinde tartışılan küresel çevresel değişimler, biyoçeşitlilik, iklim krizi ...
A. Aslı Şimşek Öner
doaj   +1 more source