Results 111 to 120 of about 5,205,037 (347)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

State primary standard of the unit of overpressure in the range of static pressure from 10 to 1600 MPa and in the range of impulse pressure

, 2023
С. М. Гаврилкин, V. M. Borovkov, A. E. Aslanyan, I. N. Temnitskii, A. Fedorov, L. V. Yurov, É. G. Aslanyan, V. V. Shvydun, A. N. Shchipunov   +8 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Integrative Approach to the Formation of Regulatory Universal Curricular Activities in Primary School Children with Learning Difficulties

Психологическая наука и образование (2007. Online), 2015
The introduction of a new state standard of primary education revealed the contradiction between the need to develop regulative universal educational actions in primary school children and the lack of specially developed psycho-pedagogical methods.
Zaitsev S.V., , Moiseva I.G.,
doaj  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Teaching the Russian language in the Second Grade in Accordance with the Federal State Educational Standard of the Primary General Education and the Federal Education Program

, 2023
Марина Кузнецова
openalex   +2 more sources

A preliminary look at techniques used to obtain airdata from flight at high angles of attack [PDF]

Flight research at high angles of attack has posed new problems for airdata measurements. New sensors and techniques for measuring the standard airdata quantities of static pressure, dynamic pressure, angle of attack, and angle of sideslip were ...
Moes, Timothy R., Whitmore, Stephen A.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Assessing the Level of Compliance to Standards among Agencies for Housing Development in Taraba State, Nigeria

Journal of Applied Sciences and Environmental Management
Housing development is an investment from which flows a number of consumer services. Hence, this paper evaluates the level of compliance to standards among agencies for housing development in Taraba State, Nigeria using both primary and secondary types ...
A. E. Chrinus, C. O. Okoye, C. Ukah
doaj   +1 more source