Results 111 to 120 of about 27,090,668 (309)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

York Ballot Audit Report - 2014 Primary Election

, 2014
This audit report by the South Carolina State Election Commission for the 2014 Primary Election in York County provides reports generated by the iVotronic voting machines and Unity election ...
South Carolina State Election Commission
core  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Bamberg 2016 Statewide Primary Election Audit Report [PDF]

, 2016
This audit report by the South Carolina State Election Commission for the 2016 Statewide Primary Election in Bamberg County provides reports generated by the iVotronic voting machines and Unity election ...
South Carolina State Election Commission
core  

Laurens Ballot Audit Report - 2014 Primary Election

, 2014
This audit report by the South Carolina State Election Commission for the 2014 Primary Election in Laurens County provides reports generated by the iVotronic voting machines and Unity election ...
South Carolina State Election Commission
core   +1 more source

UNCERTAINTY EVALUATION OF THE DISSIPATION FACTOR IN THE CALIBRATION OF PRECISION CAPACITANCE STANDARDS

Технічна електродинаміка
This paper presents a methodological and metrological approach to thecalibration of precision capacitance standards with respect to the dissipation factor (loss factor) at the State Primary Standard of Electrical Capacitance and Dissipation Factor.
S.M. Shevkun, V.P. Kvasnikov, M.V. Dobroliubova, O.V. Statsenko, M.S. Shevkun   +4 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Abbeville 2016 Statewide Primary Election Audit Report

, 2016
This audit report by the South Carolina State Election Commission for the 2016 Statewide Primary Election in Abbeville County provides reports generated by the iVotronic voting machines and Unity election ...
South Carolina State Election Commission
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source