Results 81 to 90 of about 1,753,234 (312)

Implementation Status and Optimization Strategy of Primary Care Diagnostic Coding in China [PDF]

Zhongguo quanke yixue
With the continuous deepening of the reform of the primary care and health system, the standardization of primary health information has received more and more attention.
ZHOU Yingda, QU Yiqian, LI Xiaofei, ZHUO Shuxiong, YANG Xi, JIN Hua, YU Dehua
doaj   +1 more source

State primary standard of unit of the mass concentration of oxygen, hydrogen and carbon dioxide in liquid media GET 212-2023

, 2023
A. A. Stakheev, V. I. Dobrovolskiy, T. P. Stolboushkina   +2 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Integrative Approach to the Formation of Regulatory Universal Curricular Activities in Primary School Children with Learning Difficulties

Психологическая наука и образование (2007. Online), 2015
The introduction of a new state standard of primary education revealed the contradiction between the need to develop regulative universal educational actions in primary school children and the lack of specially developed psycho-pedagogical methods.
Zaitsev S.V., , Moiseva I.G.,
doaj  

State primary standard of the unit of overpressure in the range of static pressure from 10 to 1600 MPa and in the range of impulse pressure

, 2023
С. М. Гаврилкин, V. M. Borovkov, A. E. Aslanyan, I. N. Temnitskii, A. Fedorov, L. V. Yurov, É. G. Aslanyan, V. V. Shvydun, A. N. Shchipunov   +8 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Assessing the Level of Compliance to Standards among Agencies for Housing Development in Taraba State, Nigeria

Journal of Applied Sciences and Environmental Management
Housing development is an investment from which flows a number of consumer services. Hence, this paper evaluates the level of compliance to standards among agencies for housing development in Taraba State, Nigeria using both primary and secondary types ...
A. E. Chrinus, C. O. Okoye, C. Ukah
doaj   +1 more source