Results 81 to 90 of about 1,475,612 (292)

Scalable register initialization for quantum computing in an optical lattice

open access: yes, 2003
The Mott insulator state created by loading an atomic Bose-Einstein condensate (BEC) into an optical lattice may be used as a means to prepare a register of atomic qubits in a quantum computer.
Ana Maria Rey   +6 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Optimal control of fast and high-fidelity quantum gates with electron and nuclear spins of a nitrogen-vacancy center in diamond

open access: yes, 2015
A negatively charged nitrogen vacancy (NV) center in diamond has been recognized as a good solid-state qubit. A system consisting of the electronic spin of the NV center and hyperfine-coupled nitrogen and additionally nearby carbon nuclear spins can form
Chou, Yi   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

DEMOGRAPHIC CHARACTERISTICS OF LIQUIDATORS OF CONSEQUENCES OF THE CHERNOBYL DISASTER AND PREDICTION OF THE INCIDENCE OF LEUKOSIS

open access: yesŽurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2020
Background. Changes in the size and age structure of the cohort of liquidators registered in the State Register may affect the incidence rate in the future. Objective.
Veyalkin I. V.   +3 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Event sequence detector [PDF]

open access: yes, 1973
An event sequence detector is described with input units, each associated with a row of bistable elements arranged in an array of rows and columns. The detector also includes a shift register which is responsive to clock pulses from any of the units to ...
Hanna, M. F.
core   +1 more source

Statistical Constraints on State Preparation for a Quantum Computer

open access: yes, 2002
Quantum computing algorithms require that the quantum register be initially present in a superposition state. To achieve this, we consider the practical problem of creating a coherent superposition state of several qubits.
A Ekert   +16 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Decoherence-protected quantum gates for a hybrid solid-state spin register

open access: yes, 2012
Protecting the dynamics of coupled quantum systems from decoherence by the environment is a key challenge for solid-state quantum information processing.
A Bermudez   +38 more
core   +1 more source

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