Results 171 to 180 of about 314,624 (198)

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Nonlinear segmentation and positioning of thalamic nuclei for deep brain stimulation implantation assisted by surgical robot in patients with disorders of consciousness: a technical report. [PDF]

BMC Neurol
Liu D, Cao T, Shang Y, Liu M, Sun P, Wang N, Dong Y, Guo Y, Kong D, Song Z, Liu L, Zhang G, Wong P, He S, Simpson T, Guo X, Men B, Kuang Y, Wang X, Chen G, Yin S, Yang Y.   +21 more
europepmc   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Augmented reality and 3D modeling for preoperative planning in microsurgical resection of brain arteriovenous malformations: A proof-of-concept study. [PDF]

Surg Neurol Int
Konovalov A, Kirichenko A, Okishev D, Artemyev A, Bogomazova A, Stogneva M, Sergeeva S, Erokhin I, Pilipenko Y, Grebenev F, Eliava S.   +10 more
europepmc   +1 more source

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source

Exploring new rehabilitation pathways for stroke based on the comorbidity of post-stroke hypoesthesia with anxiety and depression. [PDF]

PeerJ
Chen Y, Zhao Y, Wu B, Cheng Y, Huang J, Wang C, Bai J, Zhang Y.   +7 more
europepmc   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Clinical evaluation of free-breathing cardiac multi-parametric mapping using dictionary-based motion correction. [PDF]

Quant Imaging Med Surg
Zhao T, Chen H, Lan L, Gao J, Chen Z, He J, Xu L, Xu H, Hu C.   +8 more
europepmc   +1 more source