Results 71 to 80 of about 1,417,033 (272)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

No Match, No Vote [PDF]

, 2010
Responding to the loud wake-up call sounded in the 2000 election, Congress passed the Help America Vote Act (HAVA) in 2002, including provisions to streamline and modernize voter registration databases and establish identification requirements.

core  

Highly-efficient state-selective sub-microsecond photoionization detection of single atoms

, 2010
We experimentally demonstrate a detection scheme suitable for state analysis of single optically trapped atoms in less than 1 {\mu}s with an overall detection efficiency {\eta} exceeding 98%.
Henkel, Florian, Hofmann, Julian, Krug, Michael, Rosenfeld, Wenjamin, Weber, Markus, Weinfurter, Harald   +5 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Trend analysis and age-period-cohort effects on morbidity and mortality of liver cancer from 2010 to 2020 in Guangzhou, China

Frontiers in Oncology
IntroductionLiver cancer is one of the most common malignant gastrointestinal tumors worldwide. This study intends to provide insight into the epidemiological characteristics and development trends of liver cancer incidence and mortality from 2010 to ...
Dedong Wang, Dedong Wang, Dedong Wang, Xiangzhi Hu, Huan Xu, Yuanyuan Chen, Suixiang Wang, Guozhen Lin, Lei Yang, Jinbin Chen, Lin Zhang, Pengzhe Qin, Di Wu, Di Wu, Di Wu, Boheng Liang   +15 more
doaj   +1 more source

Corrosion Behavior of N80 Steel in CO₂ Flooding Produced Water [PDF]

Cailiao Baohu
For investigate the corrosion behavior of N80 steel at different depths of wells during production， high-temperature and highpressure reactors were used to simulate the corrosion conditions of CO2 flooding wells.The corrosion products and ...
XIE Hui, YU Chao, HUA Jing, JIANG Xiu
doaj   +1 more source

Districtly Speaking: Evenwel v. Abbott and the Apportionment Population Debate [PDF]

, 2016
The Equal Protection Clause of the Fourteenth Amendment, as interpreted by the Supreme Court, promises substantial equality of population within state legislative districts under the “one-person, one-vote” rule.
Herman, Joey
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

The Problem of the Relation of Hate and Enmity Under Article 282 Through the Prism of Publicity and Media

Сибирское юридическое обозрение, 2011
The distinction and relation of concepts of «hatred» and of «hostility». The problematic issues of qualification incite hatred or enmity are considered.
Yuliy Evgenievna Puhir
doaj  

Convex Global 3D Registration with Lagrangian Duality [PDF]

, 2017
The registration of 3D models by a Euclidean transformation is a fundamental task at the core of many application in computer vision. This problem is non-convex due to the presence of rotational constraints, making traditional local optimization methods ...
Briales, Jesus, Gonzalez-Jimenez, Antonio Javier   +1 more
core