Results 41 to 50 of about 498,088 (310)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The United Nations and 21st century security challenges in Colombia
Revista Científica General José María Córdova, 2021 Multifaceted 21st-century security challenges, such as terrorism, pandemics, illegal migration, and drug trafficking, permanently question the adequacy of both state and global organizations to guarantee general wellbeing, the rule of law, and the ...
Fredy Leonardo Galindo-García +1 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Closure Report for Corrective Action Unit 547: Miscellaneous Contaminated Waste Sites, Nevada National Security Site, Nevada [PDF]
, 2012 This Closure Report (CR) presents information supporting closure of Corrective Action Unit (CAU) 547, Miscellaneous Contaminated Waste Sites, and provides documentation supporting the completed corrective actions and confirmation that closure objectives ...
National Security Technologies, LLC
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Information security program – master policy [PDF]
, 2014 The South Carolina Budget and Control Board, Division of Information Security publishes enterprise security policies and standards to improve the state's security posture and will align information security with state agency's mission, goals and ...
South Carolina Budget and Control Board, Division of Information Security
core
, 2023 Inconsistent and unclear regulatory regimes for cloud-service providers could challenge essential cyber security protections for Australians at a time of escalating cyber incidents and geopolitical risk.
Cyber Security Cooperative Research Centre
core +1 more source
Political crime in Polish systemic conditions in the 20th century
Humanities and Social Sciences, 2020 Political offences are a specific ‘set’ of prohibited acts listed by the legislator, undertaken by the perpetrator in specific political and normative conditions, and determined by the shape of the state’s political system.
Tomasz Kuczur
doaj +1 more source
Prospects and Current Status of Defence Information Security in Ukraine
Hasanuddin Law Review, 2022 Relevance of the article - security has always been one of the priority issues of state policy. Considering that the defence forces are an inseparable part of state security, studying their information security is essential. The feasibility of this study
Olha O. Zolotar +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source