Results 51 to 60 of about 890,924 (261)

From thyroid therapy to systemic crisis: PTU-induced c-ANCA vasculitis accompanied by cold-agglutinin disease and organ failure

European Journal of Case Reports in Internal Medicine
Introduction: Propylthiouracil (PTU) is typically used as first line therapy for hyperthyroidism but is associated with a spectrum of adverse effects including vasculitis, that may lead to acute renal failure and exceptionally to pancreatitis, represents
Pelagia Kefala-Karli, Theodosia Christou, Elisavet Georgiou, Despina Pavlou, Andreas Kapouralos, Kyriakos Panagi, Konstantina Chalmoukou   +6 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Time-division prediction method for peak power of distributed new energy access power grid based on ARIMA–RBF

Sustainable Energy Research
Distributed new energy generation is influenced by various factors, resulting in high volatility and uncertainty. To enhance control, promote renewable energy consumption, and balance power supply and demand, an ARIMA–RBF-based method is proposed for ...
Yangrui Zhang, Junpeng Zhao, Chao Zhang, Bingyu Zhang, Xiaoyu Liu, Shaokang Feng   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Improved hidden Markov-graph convolutional network energy decomposition algorithm for non-invasive load monitoring

Discover Applied Sciences
Existing non-intrusive load monitoring methods often have difficulty in effectively dealing with the challenges of dynamic load fluctuations, limited generalization ability under small sample conditions, and inefficient deployment on resource-constrained
Yangrui Zhang, Chao Zhang, Yakui Zhu, Bingyu Zhang, Hongying Wang, Shaokang Feng   +5 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Genetic services in the United States [PDF]

Japanese journal of human genetics, 1994
Advances in medical genetics, including mapping of human genome, improved therapy for genetic disorders, and new screening tests for carrier detection and prenatal diagnosis, have created a growing demand for clinical genetic services in the United States.
H, Chen, W, Wertelecki
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

ENSURING THE DIGITIZATION OF PUBLIC SERVICES AS A PREREQUISITE FOR THE DEVELOPMENT OF CYBER SPACE IN THE REPUBLIC OF KAZAKHSTAN: THE EXPERIENCE OF FOREIGN COUNTRIES

Хабаршы. Заң сериясы, 2018
The urgency of the article is determined by the following factors: the acceleration of digital modern-ization in Kazakhstan under the application of global informatization leads to the transition to electronic document circulation; Increasing the ...
Useinova G.R., Ospanova D.A., Useinova K.R., Shermukhametova Zh.   +3 more
doaj  

Tamper-proof strategy of dynamic hash chain for smart grid cloud storage based on reinforcement learning key update mechanism

Discover Computing
Cloud storage systems in smart grids face dual challenges: ensuring data integrity while maintaining real-time responsiveness when managing large-scale power data.
Bo Feng, Yangrui Zhang, Chao Zhang, Bingyu Zhang, Xiaoyu Liu, Shaokang Feng   +5 more
doaj   +1 more source