Results 91 to 100 of about 963,951 (309)
Applied SciencesState space models (SSM) with selection mechanisms and hardware-aware architectures, namely Mamba, have recently shown significant potential in long-sequence modeling. Since the complexity of transformers’ self-attention mechanism is quadratic with image
Hanwei Zhang +6 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Analysis of the Impact of Energy Storage Units on Frequency Regulation Stability in Hydrothermal Power Plant Using State Space Modeling [PDF]
Hydrogen, Fuel Cell & Energy StorageEnergy storage systems have been considered in the last few years to improve the performance of energy grids. In a typical power system, an instantaneous balance between generated and consumed power must be maintained, without storing energy. As a result,
Mahnaz Hashemi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Inference for Adaptive Time Series Models: Stochastic Volatility and Conditionally Gaussian State Space Form [PDF]
In this paper we replace the Gaussian errors in the standard Gaussian, linear state space model with stochastic volatility processes. This is called a GSSF-SV model.
Neil Shephard, Charles S. Bos
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Decomposition of state-space Model with inputs: The theory and an application to estimate the ROI of advertising [PDF]
This paper shows how to compute the in-sample effect of exogenous inputs on the endogenous variables in any linear model written in state-space form. Estimating this component may be, either interesting by itself, or a previous step before decomposing a ...
Sonia Sotoca López +2 more
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
SensorsRemaining Useful Life (RUL) plays a critical role in prognostics and health management systems. It helps increase reliability and safety for the equipment used in the modern industry.
Min Li +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source