Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Forecasting VARMA processes using VAR models and subspace-based state space models
VAR modelling is a frequent technique in econometrics for linear processes. VAR modelling offers some desirable features such as relatively simple procedures for model specification (order selection) and the possibility of obtaining quick non-iterative ...
del Hoyo, Juan +2 more
core
A latent state space model for estimating brain dynamics from electroencephalogram (EEG) data. [PDF]
Biometrics, 2023 Wang Q, Loh JM, He X, Wang Y.
europepmc +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
PAT-Mamba: Adaptive all-in-one image restoration for photoacoustic tomography via state space model. [PDF]
PhotoacousticsChen Z, Feng T, Ta D.
europepmc +1 more source
Tracking the transmission dynamics of COVID-19 with a time-varying coefficient state-space model. [PDF]
Stat Med, 2022 Keller JP +4 more
europepmc +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Fast Filtering and Smoothing for Multivariate State Space Models
This paper gives a new approach to diffuse filtering and smoothing for multivariate state space models. The standard approach treats the observations as vectors while our approach treats each element of the observational vector individually.
Koopman, S.J.M., Durbin, J.
core
, 2009 In this paper a novel approach to estimate parameters in an LTI continuous-time statespace model is proposed. Essentially, the approach is based on a so-called pqR-decomposition of the numerator and denominator polynomials of the system’s transfer ...
Keesman, K.J., Khairudin, N.
core
MCAMamba: A multimodal method with bidirectional cross-attention and state space model for cancer survival prediction. [PDF]
Sci ProgCui H, Liu X, Ding W, Wang W.
europepmc +1 more source