Results 121 to 130 of about 720,413 (297)

Parameterisation and efficient MCMC estimation of non-Gaussian state space models\ud

open access: yes, 2008
The impact of parameterisation on the simulation efficiency of Bayesian Markov chain Monte Carlo (MCMC) algorithms for\ud two non-Gaussian state space models is examined.
Forbes, Catherine   +5 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Generalised Hyperbolic State-Space Models for Inference in Dynamic Systems

open access: yesIEEE Open Journal of Signal Processing
In this work we study linear vector stochastic differential equation (SDE) models driven by the generalised hyperbolic (GH) Lévy process for inference in continuous-time non-Gaussian filtering problems. The GH family of stochastic processes offers
Yaman Kindap, Simon Godsill
doaj   +1 more source

Forecasting VARMA processes using VAR models and subspace-based state space models

open access: yes
VAR modelling is a frequent technique in econometrics for linear processes. VAR modelling offers some desirable features such as relatively simple procedures for model specification (order selection) and the possibility of obtaining quick non-iterative ...
del Hoyo, Juan   +2 more
core  

Block Sampler and Posterior Mode Estimation for A Nonlinear and Non-Gaussian State-Space Model with Correlated Errors [PDF]

open access: yes
This article introduces a new efficient simulation smoother and disturbance smoother for general state-space models where there exists a correlation between error terms of the measurement and state equations.
Toshiaki Watanabe, Yasuhiro Omori
core  

Identification of nonlinear lateral flow immunoassay state-space models via particle filter approach

open access: yes, 2012
This is the post-print of the Article. The official published version can be accessed from the link below - Copyright @ 2012 IEEEIn this paper, the particle filtering approach is used, together with the kernel smoothing method, to identify the state ...
Zidong Wang   +9 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Geodesic Dynamics for Constrained State-Space Models on Riemannian Manifolds

open access: yesMathematics
We present a geodesic dynamics framework for discrete-time state evolution on the unit sphere SN−1 that maintains exact unit-norm constraints through Riemannian exponential mapping.
Tianyu Wang   +3 more
doaj   +1 more source

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