Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
NIDS-Mamba: Lightweight Network Intrusion Detection for IoT Sensor Networks via State Space Models. [PDF]
Ding Z, Zheng J, Wu X.
europepmc +1 more source
A Diagnostic Procedure for Detecting Outliers in Linear State-Space Models. [PDF]
You D, Hunter M, Chen M, Chow SM.
europepmc +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
MambaSSM: efficient segmentation of brain structures in anisotropic 3D EM images via state-space models. [PDF]
Liu M, Fang L, Zhang Q, Yang H.
europepmc +1 more source
State-space models reveal a continuing elephant poaching problem in most of Africa. [PDF]
Schlossberg S +4 more
europepmc +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
LungNet: Leveraging state-space models with SE-enhanced skip connections for precise CT-based lung lesion segmentation. [PDF]
Mi F, Xu Y, Mi S.
europepmc +1 more source
Gaussian Process State-Space Models with Time-Varying Parameters and Inducing Points. [PDF]
Liu Y, Djurić PM.
europepmc +1 more source

